Southwest Airlines
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United States
Buffalo Niagara International Airport
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United States
Midway International Airport
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Scan through all non-stop flights from Buffalo to Chicago. The full flight schedule below gives an overview of all non-stop flights from BUF to MDW, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Known for its continental climate, Chicago features hot, humid summers with temperatures above 30°C (86°F) and cold, snowy winters that often drop below 0°C (32°F). This striking seasonal contrast offers travelers a variety of activities, from summer hiking to winter sports, ensuring year-round appeal.
The best time to visit Chicago is from March to November, covering spring, summer, and fall. While summer can be hot, it also sees slightly more rainfall than other seasons.
Currently, there is only one airline operating non-stop flights from Buffalo BUF to Chicago MDW, which is Southwest Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their BUF MDW flight schedule.
Flights from BUF to MDW are operated 10 times a week, with an average of 1 flight per day. Departure times vary between 05:45 - 20:10. The earliest flight departs at 05:45, the last flight departs at 20:10. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Buffalo to Chicago takes 1 hour and 40 minutes. The flight distance between Buffalo and Chicago is 466 miles (or 750 km).
There are 2 airports in Chicago: Midway International Airport (MDW) and O'Hare International Airport (ORD).
There are 10 flights per week flying from Buffalo to Chicago (as of March 2026).
1 hour and 40 minutes is the average flight time from Buffalo to Chicago.
The distance from Buffalo to Chicago is 466 miles (750 kilometers).
Southwest Airlines is the only airline flying nonstop from Buffalo to Chicago.
There are no alliances flying direct from Buffalo to Chicago at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Buffalo to Chicago:
The earliest flight departs at 05:45 from Buffalo and arrives at 06:35 at Chicago.
The latest flight departs at 20:10 from Buffalo and arrives at 20:50 at Chicago.
466 miles (750 km) · 1h 40m
05:45
06:35
Southwest Airlines
WN 1303
Southwest Airlines
Boeing 757
Y
W
J
F
08:25
09:10
Southwest Airlines
WN 1295
Southwest Airlines
Boeing 757
Y
W
J
F
08:25
09:10
Southwest Airlines
WN 1303
Southwest Airlines
Boeing 757
Y
W
J
F
08:30
09:15
Southwest Airlines
WN 1295
Southwest Airlines
Boeing 757
Y
W
J
F
12:05
12:50
Southwest Airlines
WN 1305
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
12:15
12:55
Southwest Airlines
WN 754
Southwest Airlines
Boeing 757
Y
W
J
F
19:00
19:45
Southwest Airlines
WN 3709
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
19:35
20:15
Southwest Airlines
WN 3709
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
19:45
20:25
Southwest Airlines
WN 3709
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
20:10
20:50
Southwest Airlines
WN 1095
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
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