American Airlines
Oneworld
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United States
Ronald Reagan Washington National Airport
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United States
McGhee Tyson Airport
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Scan through all non-stop flights from Washington to Knoxville. The full flight schedule below gives an overview of all non-stop flights from DCA to TYS, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Knoxville is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Knoxville any time of the year, but the best months to explore are from to and from to .

Currently, there is only one airline operating non-stop flights from Washington DCA to Knoxville TYS, which is American Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their DCA TYS flight schedule.
Flights from DCA to TYS are operated 11 times a week, with an average of 2 flights per day. Departure times vary between 08:19 - 20:15. The earliest flight departs at 08:19, the last flight departs at 20:15. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Washington to Knoxville takes 1 hour and 44 minutes. The flight distance between Washington and Knoxville is 435 miles (or 700 km).
There is 1 airport in Knoxville: McGhee Tyson Airport (TYS).
There are 11 flights per week flying from Washington to Knoxville (as of March 2026).
1 hour and 44 minutes is the average flight time from Washington to Knoxville.
The distance from Washington to Knoxville is 435 miles (700 kilometers).
American Airlines is the only airline flying nonstop from Washington to Knoxville.
Oneworld is currently the only alliance flying nonstop from Washington to Knoxville.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Washington to Knoxville:
The earliest flight departs at 08:19 from Washington and arrives at 10:05 at Knoxville.
The latest flight departs at 20:15 from Washington and arrives at 22:00 at Knoxville.
435 miles (700 km) · 1h 44m
09:05
10:58
American Airlines
Oneworld
AA 5591
American Airlines
Canadair Regional Jet 700
Y
W
J
F
09:18
11:11
American Airlines
Oneworld
AA 5591
American Airlines
Canadair Regional Jet 700
Y
W
J
F
13:44
15:32
American Airlines
Oneworld
AA 5223
American Airlines
Canadair Regional Jet 700
Y
W
J
F
14:00
15:49
American Airlines
Oneworld
AA 5223
American Airlines
Canadair Regional Jet 900
Y
W
J
F
19:49
21:38
American Airlines
Oneworld
AA 5484
American Airlines
Canadair Regional Jet 900
Y
W
J
F
19:59
21:48
American Airlines
Oneworld
AA 5484
American Airlines
Canadair Regional Jet 900
Y
W
J
F
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