Cayman Airways
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Cayman Islands
Owen Roberts International Airport
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Panama
Tocumen International Airport
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Scan through all non-stop flights from Grand Cayman to Panama City. The full flight schedule below gives an overview of all non-stop flights from GCM to PTY, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Panama City is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Panama City experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Currently, there is only one airline operating non-stop flights from Grand Cayman GCM to Panama City PTY, which is Cayman Airways. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their GCM PTY flight schedule.
Flights from GCM to PTY are operated 3 times a week, with an average of 1 flight per day. Departure times vary between 10:10 - 16:45. The earliest flight departs at 10:10, the last flight departs at 16:45. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Grand Cayman to Panama City takes 2 hours. The flight distance between Grand Cayman and Panama City is 718 miles (or 1,156 km).
There are 3 airports in Panama City: Tocumen International Airport (PTY), Albrook "Marcos A. Gelabert" International Airport (PAC) and Howard Airport (BLB).
There are 3 flights per week flying from Grand Cayman to Panama City (as of April 2026).
2 hours is the average flight time from Grand Cayman to Panama City.
The distance from Grand Cayman to Panama City is 718 miles (1,156 kilometers).
Cayman Airways is the only airline flying nonstop from Grand Cayman to Panama City.
There are no alliances flying direct from Grand Cayman to Panama City at the moment.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Grand Cayman to Panama City:
The earliest flight departs at 10:10 from Grand Cayman and arrives at 12:10 at Panama City.
The latest flight departs at 16:45 from Grand Cayman and arrives at 18:45 at Panama City.
718 miles (1,156 km) · 2h
10:10
12:10
Cayman Airways
KX 2852
Cayman Airways
Boeing 737 MAX 8
Y
W
J
F
11:30
13:30
Cayman Airways
KX 852
Cayman Airways
Boeing 737 MAX 8
Y
W
J
F
16:45
18:45
Cayman Airways
KX 2852
Cayman Airways
Boeing 737 MAX 8
Y
W
J
F
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