Southwest Airlines
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United States
Orlando International Airport
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United States
Lambert-Saint Louis International Airport
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Scan through all non-stop flights from Orlando to St. Louis. The full flight schedule below gives an overview of all non-stop flights from MCO to STL, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
St. Louis is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit St. Louis any time of the year, but the best months to explore are from to and from to .

In total there are 2 airlines operating nonstop flights from Orlando MCO to St. Louis STL. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MCO STL flight schedule.
Flights from MCO to STL are operated 39 times a week, with an average of 6 flights per day. Departure times vary between 06:05 - 22:55. The earliest flight departs at 06:05, the last flight departs at 22:55. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Orlando to St. Louis takes 2 hours and 44 minutes. The flight distance between Orlando and St. Louis is 881 miles (or 1,418 km).
There is 1 airport in St. Louis: Lambert-Saint Louis International Airport (STL).
There are 39 flights per week flying from Orlando to St. Louis (as of May 2026).
2 hours and 44 minutes is the average flight time from Orlando to St. Louis.
The distance from Orlando to St. Louis is 881 miles (1,418 kilometers).
Frontier Airlines and Southwest Airlines are flying nonstop from Orlando to St. Louis.
There are no alliances flying direct from Orlando to St. Louis at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Orlando to St. Louis:
The earliest flight departs at 06:05 from Orlando and arrives at 07:40 at St. Louis.
The latest flight departs at 22:55 from Orlando and arrives at 00:40 at St. Louis.
881 miles (1,418 km) · 2h 44m
06:10
07:50
Southwest Airlines
WN 3208
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
06:50
08:30
Southwest Airlines
WN 3208
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
07:20
09:05
Southwest Airlines
WN 3208
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
08:05
09:50
Southwest Airlines
WN 3245
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
08:35
10:15
Southwest Airlines
WN 3245
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
08:40
10:20
Southwest Airlines
WN 261
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
08:40
10:20
Southwest Airlines
WN 261
Southwest Airlines
Boeing 757
Y
W
J
F
09:10
10:50
Southwest Airlines
WN 3245
Southwest Airlines
Boeing 757
Y
W
J
F
09:45
11:25
Southwest Airlines
WN 3208
Southwest Airlines
Boeing 757
Y
W
J
F
10:00
11:40
Southwest Airlines
WN 3245
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
10:00
11:40
Southwest Airlines
WN 3245
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
12:00
13:40
Southwest Airlines
WN 5046
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
12:15
13:55
Southwest Airlines
WN 3210
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
13:25
15:00
Southwest Airlines
WN 3210
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
13:35
15:10
Southwest Airlines
WN 3210
Southwest Airlines
Boeing 757
Y
W
J
F
13:40
15:15
Southwest Airlines
WN 3210
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
13:50
15:25
Southwest Airlines
WN 1764
Southwest Airlines
Boeing 757
Y
W
J
F
15:05
16:45
Southwest Airlines
WN 1774
Southwest Airlines
Boeing 757
Y
W
J
F
15:50
17:30
Southwest Airlines
WN 140
Southwest Airlines
Boeing 757
Y
W
J
F
16:30
18:10
Southwest Airlines
WN 3211
Southwest Airlines
Boeing 757
Y
W
J
F
17:50
19:30
Southwest Airlines
WN 3212
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
18:05
19:45
Southwest Airlines
WN 3211
Southwest Airlines
Boeing 757
Y
W
J
F
18:10
19:55
Southwest Airlines
WN 3211
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
18:15
20:00
Southwest Airlines
WN 1221
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
19:20
20:55
Southwest Airlines
WN 3211
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
19:40
21:20
Southwest Airlines
WN 3212
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
20:25
22:05
Southwest Airlines
WN 3212
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
20:55
22:35
Southwest Airlines
WN 3212
Southwest Airlines
Boeing 757
Y
W
J
F
20:55
22:35
Southwest Airlines
WN 1221
Southwest Airlines
Boeing 757
Y
W
J
F
22:00
23:40
Southwest Airlines
WN 3212
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
22:15
23:55
Southwest Airlines
WN 1221
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
22:18
23:57
Frontier Airlines
F9 2635
Frontier Airlines
Airbus A321neo
Y
W
J
F
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