Southwest Airlines
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United States
Minneapolis-Saint Paul International Airport
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United States
Lambert-Saint Louis International Airport
Click to show full flight schedule
Scan through all non-stop flights from Minneapolis to St. Louis. The full flight schedule below gives an overview of all non-stop flights from MSP to STL, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
St. Louis is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit St. Louis any time of the year, but the best months to explore are from to and from to .

In total there are 3 airlines operating nonstop flights from Minneapolis MSP to St. Louis STL. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MSP STL flight schedule.
Flights from MSP to STL are operated 44 times a week, with an average of 6 flights per day. Departure times vary between 05:45 - 21:56. The earliest flight departs at 05:45, the last flight departs at 21:56. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Minneapolis to St. Louis takes 1 hour and 37 minutes. The flight distance between Minneapolis and St. Louis is 448 miles (or 721 km).
There is 1 airport in St. Louis: Lambert-Saint Louis International Airport (STL).
There are 44 flights per week flying from Minneapolis to St. Louis (as of April 2026).
1 hour and 37 minutes is the average flight time from Minneapolis to St. Louis.
The distance from Minneapolis to St. Louis is 448 miles (721 kilometers).
Delta, Southwest Airlines and Sun Country Airlines are flying nonstop from Minneapolis to St. Louis.
SkyTeam is currently the only alliance flying nonstop from Minneapolis to St. Louis.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Minneapolis to St. Louis:
The earliest flight departs at 05:45 from Minneapolis and arrives at 07:25 at St. Louis.
The latest flight departs at 21:56 from Minneapolis and arrives at 23:31 at St. Louis.
448 miles (721 km) · 1h 37m
05:45
07:25
Southwest Airlines
WN 381
Southwest Airlines
Boeing 757
Y
W
J
F
07:00
08:46
Delta
SkyTeam
DL 4165
Delta
Embraer 175
Y
W
J
F
07:05
09:01
Delta
SkyTeam
DL 3819
Delta
Canadair Regional Jet 900
Y
W
J
F
07:25
08:55
Southwest Airlines
WN 3469
Southwest Airlines
Boeing 757
Y
W
J
F
07:50
09:20
Southwest Airlines
WN 3469
Southwest Airlines
Boeing 757
Y
W
J
F
07:55
09:35
Southwest Airlines
WN 381
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
07:55
09:35
Southwest Airlines
WN 381
Southwest Airlines
Boeing 757
Y
W
J
F
08:00
09:30
Southwest Airlines
WN 3469
Southwest Airlines
Boeing 757
Y
W
J
F
08:05
09:35
Southwest Airlines
WN 3469
Southwest Airlines
Boeing 757
Y
W
J
F
10:00
11:39
Delta
SkyTeam
DL 4858
Delta
Canadair Regional Jet 900
Y
W
J
F
10:00
11:39
Delta
SkyTeam
DL 3858
Delta
Canadair Regional Jet 900
Y
W
J
F
10:00
11:32
Delta
SkyTeam
DL 2884
Delta
Airbus A220-100
Y
W
J
F
10:00
11:39
Delta
SkyTeam
DL 4858
Delta
Canadair Regional Jet 900
Y
W
J
F
10:04
11:43
Delta
SkyTeam
DL 4858
Delta
Canadair Regional Jet 900
Y
W
J
F
10:05
11:48
Delta
SkyTeam
DL 3884
Delta
Canadair Regional Jet 900
Y
W
J
F
12:45
14:24
Delta
SkyTeam
DL 3921
Delta
Canadair Regional Jet 900
Y
W
J
F
12:50
14:29
Delta
SkyTeam
DL 3870
Delta
Canadair Regional Jet 900
Y
W
J
F
14:45
16:15
Southwest Airlines
WN 3470
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
15:18
16:50
Delta
SkyTeam
DL 1605
Delta
Boeing 717
Y
W
J
F
15:18
16:50
Delta
SkyTeam
DL 1605
Delta
Boeing 717
Y
W
J
F
15:30
17:05
Delta
SkyTeam
DL 1605
Delta
Boeing 717
Y
W
J
F
15:30
17:05
Delta
SkyTeam
DL 1605
Delta
Boeing 717
Y
W
J
F
15:30
17:08
Delta
SkyTeam
DL 4705
Delta
Canadair Regional Jet 900
Y
W
J
F
16:30
18:00
Southwest Airlines
WN 3470
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
17:20
18:50
Southwest Airlines
WN 3470
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
17:30
18:55
Southwest Airlines
WN 1871
Southwest Airlines
Boeing 757
Y
W
J
F
21:39
23:14
Delta
SkyTeam
DL 1609
Delta
Airbus A321-100/200
Y
W
J
F
21:39
23:14
Delta
SkyTeam
DL 1609
Delta
Airbus A321-100/200
Y
W
J
F
21:39
23:13
Delta
SkyTeam
DL 1609
Delta
Airbus A319
Y
W
J
F
21:39
23:13
Delta
SkyTeam
DL 1609
Delta
Airbus A319
Y
W
J
F
21:50
23:25
Delta
SkyTeam
DL 1609
Delta
Airbus A220-100
Y
W
J
F
21:50
23:25
Delta
SkyTeam
DL 1609
Delta
Airbus A220-100
Y
W
J
F
21:56
23:31
Delta
SkyTeam
DL 1609
Delta
Boeing 737-900
Y
W
J
F
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