Southwest Airlines
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United States
Southwest Florida International Airport
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United States
Buffalo Niagara International Airport
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Scan through all non-stop flights from Fort Myers to Buffalo. The full flight schedule below gives an overview of all non-stop flights from RSW to BUF, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Warm Continental destinations such as Buffalo enjoy summer temperatures that fluctuate between 20°C and 28°C (68°F to 82°F), with some heatwaves leading to even hotter days. Winters are mostly cold and snowy, with average temperatures ranging from -5°C to 0°C (23°F to 32°F). Travelers can enjoy the vibrant autumn scenery, ski during the winter season, or enjoy the comfortable to warm summer months.
If you're planning a trip to Buffalo, the best time to visit is from late spring through the end of summer, when the weather is pleasantly warm from May to August. Winters can be quite cold, with frost occurring almost every month from November to March and regular snowfall. This makes the mountainous regions perfect for winter sports, offering great opportunities for a winter getaway as well!
In total there are 2 airlines operating nonstop flights from Fort Myers RSW to Buffalo BUF. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their RSW BUF flight schedule.
Flights from RSW to BUF are operated twice a week. Departure times vary between 08:05 - 20:30. The earliest flight departs at 08:05, the last flight departs at 20:30. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Fort Myers to Buffalo takes 2 hours and 49 minutes. The flight distance between Fort Myers and Buffalo is 1,145 miles (or 1,843 km).
There is 1 airport in Buffalo: Buffalo Niagara International Airport (BUF).
There are 2 flights per week flying from Fort Myers to Buffalo (as of March 2026).
2 hours and 49 minutes is the average flight time from Fort Myers to Buffalo.
The distance from Fort Myers to Buffalo is 1,145 miles (1,843 kilometers).
JetBlue and Southwest Airlines are flying nonstop from Fort Myers to Buffalo.
There are no alliances flying direct from Fort Myers to Buffalo at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Fort Myers to Buffalo:
The earliest flight departs at 08:05 from Fort Myers and arrives at 10:55 at Buffalo.
The latest flight departs at 20:30 from Fort Myers and arrives at 23:20 at Buffalo.
1,145 miles (1,843 km) · 2h 49m
08:05
10:55
Southwest Airlines
WN 1404
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
09:10
12:00
Southwest Airlines
WN 1404
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
15:50
18:39
JetBlue
B6 2050
JetBlue
Airbus A320-100/200
Y
W
J
F
20:30
23:20
Southwest Airlines
WN 4608
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
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