Allegiant
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United States
Southwest Florida International Airport
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United States
Des Moines International Airport
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Scan through all non-stop flights from Fort Myers to Des Moines. The full flight schedule below gives an overview of all non-stop flights from RSW to DSM, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Known for its continental climate, Des Moines features hot, humid summers with temperatures above 30°C (86°F) and cold, snowy winters that often drop below 0°C (32°F). This striking seasonal contrast offers travelers a variety of activities, from summer hiking to winter sports, ensuring year-round appeal.
The best time to visit Des Moines is from March to November, covering spring, summer, and fall. While summer can be hot, it also sees slightly more rainfall than other seasons.
Currently, there is only one airline operating non-stop flights from Fort Myers RSW to Des Moines DSM, which is Allegiant. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their RSW DSM flight schedule.
Flights from RSW to DSM are operated twice a week. Departure times vary between 10:54 - 20:00. The earliest flight departs at 10:54, the last flight departs at 20:00. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Fort Myers to Des Moines takes 3 hours and 19 minutes. The flight distance between Fort Myers and Des Moines is 1,236 miles (or 1,989 km).
There is 1 airport in Des Moines: Des Moines International Airport (DSM).
There are 2 flights per week flying from Fort Myers to Des Moines (as of April 2026).
3 hours and 19 minutes is the average flight time from Fort Myers to Des Moines.
The distance from Fort Myers to Des Moines is 1,236 miles (1,989 kilometers).
Allegiant is the only airline flying nonstop from Fort Myers to Des Moines.
There are no alliances flying direct from Fort Myers to Des Moines at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Fort Myers to Des Moines:
The earliest flight departs at 10:54 from Fort Myers and arrives at 13:13 at Des Moines.
The latest flight departs at 20:00 from Fort Myers and arrives at 22:15 at Des Moines.
1,236 miles (1,989 km) · 3h 19m
10:54
13:13
Allegiant
G4 432
Allegiant
Airbus A320-100/200
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W
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F
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