Southwest Airlines
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United States
San Antonio International Airport
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United States
Lambert-Saint Louis International Airport
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Scan through all non-stop flights from San Antonio to St. Louis. The full flight schedule below gives an overview of all non-stop flights from SAT to STL, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
St. Louis is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit St. Louis any time of the year, but the best months to explore are from to and from to .

Currently, there is only one airline operating non-stop flights from San Antonio SAT to St. Louis STL, which is Southwest Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their SAT STL flight schedule.
Flights from SAT to STL are operated 13 times a week, with an average of 2 flights per day. Departure times vary between 05:40 - 17:00. The earliest flight departs at 05:40, the last flight departs at 17:00. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from San Antonio to St. Louis takes 2 hours and 10 minutes. The flight distance between San Antonio and St. Louis is 786 miles (or 1,265 km).
There is 1 airport in St. Louis: Lambert-Saint Louis International Airport (STL).
There are 13 flights per week flying from San Antonio to St. Louis (as of April 2026).
2 hours and 10 minutes is the average flight time from San Antonio to St. Louis.
The distance from San Antonio to St. Louis is 786 miles (1,265 kilometers).
Southwest Airlines is the only airline flying nonstop from San Antonio to St. Louis.
There are no alliances flying direct from San Antonio to St. Louis at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from San Antonio to St. Louis:
The earliest flight departs at 05:40 from San Antonio and arrives at 07:45 at St. Louis.
The latest flight departs at 17:00 from San Antonio and arrives at 19:10 at St. Louis.
786 miles (1,265 km) · 2h 10m
07:20
09:30
Southwest Airlines
WN 849
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
07:20
09:30
Southwest Airlines
WN 849
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
07:25
09:35
Southwest Airlines
WN 1436
Southwest Airlines
Boeing 757
Y
W
J
F
07:30
09:35
Southwest Airlines
WN 4404
Southwest Airlines
Boeing 757
Y
W
J
F
07:30
09:35
Southwest Airlines
WN 4404
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
07:40
09:50
Southwest Airlines
WN 1436
Southwest Airlines
Boeing 757
Y
W
J
F
15:50
18:00
Southwest Airlines
WN 4175
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
16:40
18:50
Southwest Airlines
WN 4406
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
16:45
18:55
Southwest Airlines
WN 4406
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
16:45
18:55
Southwest Airlines
WN 4175
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
17:00
19:10
Southwest Airlines
WN 1436
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
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