American Airlines
Oneworld
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Louisville International Airport (Standiford Field)
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John Wayne Airport
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Scan through all non-stop flights from Louisville to Santa Ana. The full flight schedule below gives an overview of all non-stop flights from SDF to SNA, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
The Mediterranean regions near Santa Ana are known for their warm, arid summers, where temperatures often go beyond 30°C (86°F). In some inland spots, the heat can climb even higher, sometimes reaching 40°C (104°F) or more. The winters are pleasantly mild, accompanied by some rainfall. This lovely climate, paired with breathtaking landscapes and bright, sunny days attract visitors from around the globe.
Santa Ana is a wonderful place to visit all year long, but spring (March-May) and fall (September-November) are the best seasons to visit. The weather is pleasantly warm during these times, especially since the summers can be quite hot in those regions.

Currently, there is only one airline operating non-stop flights from Louisville SDF to Santa Ana SNA, which is American Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their SDF SNA flight schedule.
All flights depart at 11:09.
You can fly in Economy, Business Class and First Class. Premium Economy is not available on this route (at least not as a non-stop flight).
The fastest direct flight from Louisville to Santa Ana takes 5 hours and 5 minutes. The flight distance between Louisville and Santa Ana is 1,814 miles (or 2,919 km).
There are 2 airports in Santa Ana: John Wayne Airport (SNA) and Santa Monica Airport (SMO).
There are 0 flights per week flying from Louisville to Santa Ana (as of April 2026).
5 hours and 5 minutes is the average flight time from Louisville to Santa Ana.
The distance from Louisville to Santa Ana is 1,814 miles (2,919 kilometers).
American Airlines is the only airline flying nonstop from Louisville to Santa Ana.
Oneworld is currently the only alliance flying nonstop from Louisville to Santa Ana.
You can fly non-stop in Economy, Business Class and First Class.
Aircraft types that fly from Louisville to Santa Ana:
The earliest flight departs at 11:09 from Louisville and arrives at 13:14 at Santa Ana.
The latest flight departs at 11:09 from Louisville and arrives at 13:14 at Santa Ana.
1,814 miles (2,919 km) · 5h 5m
11:09
13:14
American Airlines
Oneworld
AA 3275
American Airlines
Airbus A321 (sharklets)
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