Copa Airlines
Star Alliance
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Dominican Republic
Las Américas International Airport
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Panama
Tocumen International Airport
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Scan through all non-stop flights from Santo Domingo to Panama City. The full flight schedule below gives an overview of all non-stop flights from SDQ to PTY, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Panama City is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Panama City experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Currently, there is only one airline operating non-stop flights from Santo Domingo SDQ to Panama City PTY, which is Copa Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their SDQ PTY flight schedule.
Flights from SDQ to PTY are operated 3 times a week, with an average of 1 flight per day. Departure times vary between 06:00 - 18:42. The earliest flight departs at 06:00, the last flight departs at 18:42. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Santo Domingo to Panama City takes 2 hours and 44 minutes. The flight distance between Santo Domingo and Panama City is 917 miles (or 1,476 km).
There are 3 airports in Panama City: Tocumen International Airport (PTY), Albrook "Marcos A. Gelabert" International Airport (PAC) and Howard Airport (BLB).
There are 3 flights per week flying from Santo Domingo to Panama City (as of March 2026).
2 hours and 44 minutes is the average flight time from Santo Domingo to Panama City.
The distance from Santo Domingo to Panama City is 917 miles (1,476 kilometers).
Copa Airlines is the only airline flying nonstop from Santo Domingo to Panama City.
Star Alliance is currently the only alliance flying nonstop from Santo Domingo to Panama City.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Santo Domingo to Panama City:
The earliest flight departs at 06:00 from Santo Domingo and arrives at 07:42 at Panama City.
The latest flight departs at 18:42 from Santo Domingo and arrives at 20:14 at Panama City.
917 miles (1,476 km) · 2h 44m
06:01
07:39
Copa Airlines
Star Alliance
CM 108
Copa Airlines
Boeing 737-700
Y
W
J
F
08:37
10:20
Copa Airlines
Star Alliance
CM 267
Copa Airlines
Boeing 737-800
Y
W
J
F
12:41
14:15
Copa Airlines
Star Alliance
CM 129
Copa Airlines
Boeing 737 MAX 8
Y
W
J
F
14:12
15:49
Copa Airlines
Star Alliance
CM 299
Copa Airlines
Boeing 737-800
Y
W
J
F
18:41
20:14
Copa Airlines
Star Alliance
CM 464
Copa Airlines
Boeing 737 MAX 8
Y
W
J
F
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