Allegiant
Did you mean flights from Knoxville to Destin / Fort Walton Beach?
United States
Northwest Florida Regional Airport / Eglin Air Force Ba
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United States
McGhee Tyson Airport
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Scan through all non-stop flights from Destin / Fort Walton Beach to Knoxville. The full flight schedule below gives an overview of all non-stop flights from VPS to TYS, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Knoxville is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Knoxville any time of the year, but the best months to explore are from to and from to .
Currently, there is only one airline operating non-stop flights from Destin / Fort Walton Beach VPS to Knoxville TYS, which is Allegiant. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their VPS TYS flight schedule.
Flights from VPS to TYS are operated twice a week. Departure times vary between 07:16 - 21:14. The earliest flight departs at 07:16, the last flight departs at 21:14. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Destin / Fort Walton Beach to Knoxville takes 1 hour and 21 minutes. The flight distance between Destin / Fort Walton Beach and Knoxville is 395 miles (or 636 km).
There is 1 airport in Knoxville: McGhee Tyson Airport (TYS).
There are 2 flights per week flying from Destin / Fort Walton Beach to Knoxville (as of April 2026).
1 hour and 21 minutes is the average flight time from Destin / Fort Walton Beach to Knoxville.
The distance from Destin / Fort Walton Beach to Knoxville is 395 miles (636 kilometers).
Allegiant is the only airline flying nonstop from Destin / Fort Walton Beach to Knoxville.
There are no alliances flying direct from Destin / Fort Walton Beach to Knoxville at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Destin / Fort Walton Beach to Knoxville:
The earliest flight departs at 07:16 from Destin / Fort Walton Beach and arrives at 09:37 at Knoxville.
The latest flight departs at 21:14 from Destin / Fort Walton Beach and arrives at 23:35 at Knoxville.
395 miles (636 km) · 1h 21m
07:16
09:37
Allegiant
G4 1425
Allegiant
Airbus A320-100/200
Y
W
J
F
08:16
10:37
Allegiant
G4 3024
Allegiant
Airbus A320-100/200
Y
W
J
F
08:16
10:37
Allegiant
G4 3042
Allegiant
Airbus A320-100/200
Y
W
J
F
11:01
13:22
Allegiant
G4 1439
Allegiant
Airbus A320-100/200
Y
W
J
F
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