American Airlines
Oneworld
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Charlotte/Douglas International Airport
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United States
Buffalo Niagara International Airport
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Scan through all non-stop flights from Charlotte to Buffalo. The full flight schedule below gives an overview of all non-stop flights from CLT to BUF, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Warm Continental destinations such as Buffalo enjoy summer temperatures that fluctuate between 20°C and 28°C (68°F to 82°F), with some heatwaves leading to even hotter days. Winters are mostly cold and snowy, with average temperatures ranging from -5°C to 0°C (23°F to 32°F). Travelers can enjoy the vibrant autumn scenery, ski during the winter season, or enjoy the comfortable to warm summer months.
If you're planning a trip to Buffalo, the best time to visit is from late spring through the end of summer, when the weather is pleasantly warm from May to August. Winters can be quite cold, with frost occurring almost every month from November to March and regular snowfall. This makes the mountainous regions perfect for winter sports, offering great opportunities for a winter getaway as well!

Currently, there is only one airline operating non-stop flights from Charlotte CLT to Buffalo BUF, which is American Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their CLT BUF flight schedule.
Flights from CLT to BUF are operated 6 times a week, with an average of 1 flight per day. Departure times vary between 07:20 - 22:26. The earliest flight departs at 07:20, the last flight departs at 22:26. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Charlotte to Buffalo takes 1 hour and 47 minutes. The flight distance between Charlotte and Buffalo is 546 miles (or 879 km).
There is 1 airport in Buffalo: Buffalo Niagara International Airport (BUF).
There are 6 flights per week flying from Charlotte to Buffalo (as of March 2026).
1 hour and 47 minutes is the average flight time from Charlotte to Buffalo.
The distance from Charlotte to Buffalo is 546 miles (879 kilometers).
American Airlines is the only airline flying nonstop from Charlotte to Buffalo.
Oneworld is currently the only alliance flying nonstop from Charlotte to Buffalo.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Charlotte to Buffalo:
The earliest flight departs at 07:20 from Charlotte and arrives at 09:03 at Buffalo.
The latest flight departs at 22:26 from Charlotte and arrives at 00:09 at Buffalo.
546 miles (879 km) · 1h 47m
11:01
12:51
American Airlines
Oneworld
AA 1203
American Airlines
Airbus A319
Y
W
J
F
11:05
12:55
American Airlines
Oneworld
AA 1203
American Airlines
Airbus A319
Y
W
J
F
16:04
17:54
American Airlines
Oneworld
AA 1621
American Airlines
Airbus A320-100/200
Y
W
J
F
16:55
18:45
American Airlines
Oneworld
AA 2301
American Airlines
Airbus A319
Y
W
J
F
17:23
19:11
American Airlines
Oneworld
AA 2301
American Airlines
Airbus A319
Y
W
J
F
21:40
23:28
American Airlines
Oneworld
AA 2429
American Airlines
Airbus A321-100/200
Y
W
J
F
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