American Airlines
Oneworld
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Charlotte/Douglas International Airport
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United States
Key West International Airport
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Scan through all non-stop flights from Charlotte to Key West. The full flight schedule below gives an overview of all non-stop flights from CLT to EYW, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Key West is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Key West experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Currently, there is only one airline operating non-stop flights from Charlotte CLT to Key West EYW, which is American Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their CLT EYW flight schedule.
Flights from CLT to EYW are operated 26 times a week, with an average of 4 flights per day. Departure times vary between 08:55 - 20:23. The earliest flight departs at 08:55, the last flight departs at 20:23. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Charlotte to Key West takes 2 hours and 22 minutes. The flight distance between Charlotte and Key West is 737 miles (or 1,186 km).
There is 1 airport in Key West: Key West International Airport (EYW).
There are 26 flights per week flying from Charlotte to Key West (as of April 2026).
2 hours and 22 minutes is the average flight time from Charlotte to Key West.
The distance from Charlotte to Key West is 737 miles (1,186 kilometers).
American Airlines is the only airline flying nonstop from Charlotte to Key West.
Oneworld is currently the only alliance flying nonstop from Charlotte to Key West.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Charlotte to Key West:
The earliest flight departs at 08:55 from Charlotte and arrives at 11:11 at Key West.
The latest flight departs at 20:23 from Charlotte and arrives at 22:37 at Key West.
737 miles (1,186 km) · 2h 22m
08:55
11:11
American Airlines
Oneworld
AA 2199
American Airlines
Airbus A319
Y
W
J
F
08:55
11:16
American Airlines
Oneworld
AA 2076
American Airlines
Airbus A319
Y
W
J
F
11:00
13:26
American Airlines
Oneworld
AA 2839
American Airlines
Airbus A319
Y
W
J
F
11:00
13:21
American Airlines
Oneworld
AA 2073
American Airlines
Airbus A319
Y
W
J
F
13:25
15:40
American Airlines
Oneworld
AA 2077
American Airlines
Airbus A319
Y
W
J
F
13:35
15:57
American Airlines
Oneworld
AA 1818
American Airlines
Airbus A319
Y
W
J
F
13:58
16:13
American Airlines
Oneworld
AA 2077
American Airlines
Airbus A319
Y
W
J
F
14:20
16:35
American Airlines
Oneworld
AA 2077
American Airlines
Airbus A319
Y
W
J
F
19:38
21:53
American Airlines
Oneworld
AA 642
American Airlines
Airbus A319
Y
W
J
F
20:23
22:37
American Airlines
Oneworld
AA 1365
American Airlines
Airbus A319
Y
W
J
F
20:23
22:36
American Airlines
Oneworld
AA 642
American Airlines
Airbus A319
Y
W
J
F
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