American Airlines
Oneworld
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United States
Charlotte/Douglas International Airport
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United States
Lambert-Saint Louis International Airport
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Scan through all non-stop flights from Charlotte to St. Louis. The full flight schedule below gives an overview of all non-stop flights from CLT to STL, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
St. Louis is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit St. Louis any time of the year, but the best months to explore are from to and from to .

In total there are 2 airlines operating nonstop flights from Charlotte CLT to St. Louis STL. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their CLT STL flight schedule.
Flights from CLT to STL are operated 29 times a week, with an average of 4 flights per day. Departure times vary between 07:05 - 22:55. The earliest flight departs at 07:05, the last flight departs at 22:55. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Charlotte to St. Louis takes 1 hour and 59 minutes. The flight distance between Charlotte and St. Louis is 574 miles (or 924 km).
There is 1 airport in St. Louis: Lambert-Saint Louis International Airport (STL).
There are 29 flights per week flying from Charlotte to St. Louis (as of April 2026).
1 hour and 59 minutes is the average flight time from Charlotte to St. Louis.
The distance from Charlotte to St. Louis is 574 miles (924 kilometers).
American Airlines and Southwest Airlines are flying nonstop from Charlotte to St. Louis.
Oneworld is currently the only alliance flying nonstop from Charlotte to St. Louis.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Charlotte to St. Louis:
The earliest flight departs at 07:05 from Charlotte and arrives at 08:02 at St. Louis.
The latest flight departs at 22:55 from Charlotte and arrives at 23:57 at St. Louis.
574 miles (924 km) · 1h 59m
07:26
08:30
American Airlines
Oneworld
AA 2950
American Airlines
Airbus A319
Y
W
J
F
07:30
08:35
American Airlines
Oneworld
AA 2475
American Airlines
Airbus A319
Y
W
J
F
08:40
09:44
American Airlines
Oneworld
AA 2950
American Airlines
Airbus A319
Y
W
J
F
11:37
12:43
American Airlines
Oneworld
AA 2486
American Airlines
Boeing 737-800
Y
W
J
F
11:37
12:42
American Airlines
Oneworld
AA 2486
American Airlines
Airbus A319
Y
W
J
F
12:21
13:22
American Airlines
Oneworld
AA 2958
American Airlines
Boeing 737-800
Y
W
J
F
12:50
13:55
Southwest Airlines
WN 4394
Southwest Airlines
Boeing 757
Y
W
J
F
13:32
14:33
American Airlines
Oneworld
AA 2958
American Airlines
Boeing 737-800
Y
W
J
F
15:58
17:03
American Airlines
Oneworld
AA 2943
American Airlines
Boeing 737 MAX 8
Y
W
J
F
16:45
17:49
American Airlines
Oneworld
AA 2943
American Airlines
Airbus A319
Y
W
J
F
16:58
18:07
American Airlines
Oneworld
AA 2477
American Airlines
Boeing 737 MAX 8
Y
W
J
F
16:59
18:04
American Airlines
Oneworld
AA 2943
American Airlines
Boeing 737 MAX 8
Y
W
J
F
17:01
18:07
American Airlines
Oneworld
AA 2477
American Airlines
Airbus A319
Y
W
J
F
18:25
19:30
American Airlines
Oneworld
AA 2937
American Airlines
Boeing 737-800
Y
W
J
F
18:26
19:30
American Airlines
Oneworld
AA 2477
American Airlines
Boeing 737-800
Y
W
J
F
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