Southwest Airlines
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Denver International Airport
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United States
Northwest Florida Beaches International Airport
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Scan through all non-stop flights from Denver to Panama City. The full flight schedule below gives an overview of all non-stop flights from DEN to ECP, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Panama City is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Panama City any time of the year, but the best months to explore are from to and from to .

In total there are 2 airlines operating nonstop flights from Denver DEN to Panama City ECP. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their DEN ECP flight schedule.
Flights from DEN to ECP are operated 4 times a week, with an average of 1 flight per day. Departure times vary between 10:00 - 17:55. The earliest flight departs at 10:00, the last flight departs at 17:55. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Denver to Panama City takes 2 hours and 45 minutes. The flight distance between Denver and Panama City is 1,248 miles (or 2,008 km).
There is 1 airport in Panama City: Northwest Florida Beaches International Airport (ECP).
There are 4 flights per week flying from Denver to Panama City (as of March 2026).
2 hours and 45 minutes is the average flight time from Denver to Panama City.
The distance from Denver to Panama City is 1,248 miles (2,008 kilometers).
Southwest Airlines and United Airlines are flying nonstop from Denver to Panama City.
Star Alliance is currently the only alliance flying nonstop from Denver to Panama City.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Denver to Panama City:
The earliest flight departs at 10:00 from Denver and arrives at 14:21 at Panama City.
The latest flight departs at 17:55 from Denver and arrives at 22:00 at Panama City.
1,248 miles (2,008 km) · 2h 45m
10:45
14:35
Southwest Airlines
WN 266
Southwest Airlines
Boeing 757
Y
W
J
F
11:00
14:50
Southwest Airlines
WN 266
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
12:00
15:50
Southwest Airlines
WN 266
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
12:35
16:20
Southwest Airlines
WN 266
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
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