Southwest Airlines
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United States
Detroit Metropolitan Wayne County Airport
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United States
Lambert-Saint Louis International Airport
Click to show full flight schedule
Scan through all non-stop flights from Detroit to St. Louis. The full flight schedule below gives an overview of all non-stop flights from DTW to STL, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
St. Louis is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit St. Louis any time of the year, but the best months to explore are from to and from to .
In total there are 2 airlines operating nonstop flights from Detroit DTW to St. Louis STL. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their DTW STL flight schedule.
Flights from DTW to STL are operated 39 times a week, with an average of 6 flights per day. Departure times vary between 06:25 - 20:30. The earliest flight departs at 06:25, the last flight departs at 20:30. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Detroit to St. Louis takes 1 hour and 39 minutes. The flight distance between Detroit and St. Louis is 439 miles (or 707 km).
There is 1 airport in St. Louis: Lambert-Saint Louis International Airport (STL).
There are 39 flights per week flying from Detroit to St. Louis (as of April 2026).
1 hour and 39 minutes is the average flight time from Detroit to St. Louis.
The distance from Detroit to St. Louis is 439 miles (707 kilometers).
Delta and Southwest Airlines are flying nonstop from Detroit to St. Louis.
SkyTeam is currently the only alliance flying nonstop from Detroit to St. Louis.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Detroit to St. Louis:
The earliest flight departs at 06:25 from Detroit and arrives at 07:00 at St. Louis.
The latest flight departs at 20:30 from Detroit and arrives at 21:10 at St. Louis.
439 miles (707 km) · 1h 39m
07:00
07:45
Southwest Airlines
WN 2867
Southwest Airlines
Boeing 757
Y
W
J
F
07:00
07:45
Southwest Airlines
WN 2361
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
07:00
07:45
Southwest Airlines
WN 2361
Southwest Airlines
Boeing 757
Y
W
J
F
07:20
08:00
Southwest Airlines
WN 2361
Southwest Airlines
Boeing 757
Y
W
J
F
08:59
09:46
Delta
SkyTeam
DL 3863
Delta
Canadair Regional Jet 900
Y
W
J
F
08:59
09:46
Delta
SkyTeam
DL 3863
Delta
Canadair Regional Jet 900
Y
W
J
F
08:59
09:42
Delta
SkyTeam
DL 2868
Delta
Boeing 717
Y
W
J
F
08:59
09:48
Delta
SkyTeam
DL 3568
Delta
Canadair Regional Jet 900
Y
W
J
F
12:18
12:58
Delta
SkyTeam
DL 3739
Delta
Canadair Regional Jet 900
Y
W
J
F
12:18
12:58
Delta
SkyTeam
DL 3739
Delta
Canadair Regional Jet 900
Y
W
J
F
12:20
13:05
Delta
SkyTeam
DL 3854
Delta
Canadair Regional Jet 900
Y
W
J
F
15:40
16:20
Southwest Airlines
WN 692
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
15:50
16:32
Delta
SkyTeam
DL 2822
Delta
Boeing 717
Y
W
J
F
15:50
16:32
Delta
SkyTeam
DL 2822
Delta
Boeing 717
Y
W
J
F
15:50
16:32
Delta
SkyTeam
DL 2822
Delta
Boeing 717
Y
W
J
F
16:00
16:40
Delta
SkyTeam
DL 4822
Delta
Canadair Regional Jet 900
Y
W
J
F
16:00
16:42
Delta
SkyTeam
DL 2822
Delta
Boeing 717
Y
W
J
F
16:00
16:42
Delta
SkyTeam
DL 2822
Delta
Boeing 717
Y
W
J
F
19:10
19:55
Southwest Airlines
WN 692
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
19:15
19:55
Southwest Airlines
WN 2869
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
20:00
20:42
Delta
SkyTeam
DL 1541
Delta
Boeing 717
Y
W
J
F
20:00
20:42
Delta
SkyTeam
DL 1541
Delta
Boeing 717
Y
W
J
F
20:00
20:42
Delta
SkyTeam
DL 1541
Delta
Boeing 717
Y
W
J
F
20:02
20:44
Delta
SkyTeam
DL 1541
Delta
Boeing 717
Y
W
J
F
20:02
20:44
Delta
SkyTeam
DL 1541
Delta
Boeing 717
Y
W
J
F
20:10
20:55
Southwest Airlines
WN 2869
Southwest Airlines
Boeing 757
Y
W
J
F
20:15
20:55
Southwest Airlines
WN 692
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
20:30
21:10
Southwest Airlines
WN 878
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
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