Allegiant
Did you mean flights from Knoxville to Key West?
United States
Key West International Airport
Switch direction
United States
McGhee Tyson Airport
Click to show full flight schedule
Scan through all non-stop flights from Key West to Knoxville. The full flight schedule below gives an overview of all non-stop flights from EYW to TYS, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Knoxville is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Knoxville any time of the year, but the best months to explore are from to and from to .
Currently, there is only one airline operating non-stop flights from Key West EYW to Knoxville TYS, which is Allegiant. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their EYW TYS flight schedule.
Flights from EYW to TYS are operated twice a week. Departure times vary between 09:01 - 11:54. The earliest flight departs at 09:01, the last flight departs at 11:54. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Key West to Knoxville takes 2 hours and 15 minutes. The flight distance between Key West and Knoxville is 788 miles (or 1,268 km).
There is 1 airport in Knoxville: McGhee Tyson Airport (TYS).
There are 2 flights per week flying from Key West to Knoxville (as of April 2026).
2 hours and 15 minutes is the average flight time from Key West to Knoxville.
The distance from Key West to Knoxville is 788 miles (1,268 kilometers).
Allegiant is the only airline flying nonstop from Key West to Knoxville.
There are no alliances flying direct from Key West to Knoxville at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Key West to Knoxville:
The earliest flight departs at 09:01 from Key West and arrives at 11:16 at Knoxville.
The latest flight departs at 11:54 from Key West and arrives at 14:07 at Knoxville.
788 miles (1,268 km) · 2h 15m
11:01
13:16
Allegiant
G4 1397
Allegiant
Airbus A320-100/200
Y
W
J
F
Click to Check Prices
