Southwest Airlines
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United States
William P. Hobby Airport
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United States
Lambert-Saint Louis International Airport
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Scan through all non-stop flights from Houston to St. Louis. The full flight schedule below gives an overview of all non-stop flights from HOU to STL, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
St. Louis is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit St. Louis any time of the year, but the best months to explore are from to and from to .

Currently, there is only one airline operating non-stop flights from Houston HOU to St. Louis STL, which is Southwest Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their HOU STL flight schedule.
Flights from HOU to STL are operated 29 times a week, with an average of 4 flights per day. Departure times vary between 05:30 - 22:40. The earliest flight departs at 05:30, the last flight departs at 22:40. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Houston to St. Louis takes 2 hours. The flight distance between Houston and St. Louis is 688 miles (or 1,107 km).
There is 1 airport in St. Louis: Lambert-Saint Louis International Airport (STL).
There are 29 flights per week flying from Houston to St. Louis (as of April 2026).
2 hours is the average flight time from Houston to St. Louis.
The distance from Houston to St. Louis is 688 miles (1,107 kilometers).
Southwest Airlines is the only airline flying nonstop from Houston to St. Louis.
There are no alliances flying direct from Houston to St. Louis at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Houston to St. Louis:
The earliest flight departs at 05:30 from Houston and arrives at 07:30 at St. Louis.
The latest flight departs at 22:40 from Houston and arrives at 00:40 at St. Louis.
688 miles (1,107 km) · 2h
07:25
09:25
Southwest Airlines
WN 2422
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
07:30
09:25
Southwest Airlines
WN 344
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
07:35
09:35
Southwest Airlines
WN 2422
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
07:35
09:35
Southwest Airlines
WN 2422
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
07:35
09:35
Southwest Airlines
WN 2422
Southwest Airlines
Boeing 757
Y
W
J
F
07:40
09:35
Southwest Airlines
WN 344
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
09:30
11:30
Southwest Airlines
WN 3313
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
09:50
11:50
Southwest Airlines
WN 968
Southwest Airlines
Boeing 757
Y
W
J
F
10:25
12:25
Southwest Airlines
WN 498
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
10:30
12:30
Southwest Airlines
WN 498
Southwest Airlines
Boeing 757
Y
W
J
F
10:40
12:40
Southwest Airlines
WN 3153
Southwest Airlines
Boeing 757
Y
W
J
F
11:05
13:05
Southwest Airlines
WN 3854
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
13:05
15:05
Southwest Airlines
WN 3315
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
13:15
15:15
Southwest Airlines
WN 3315
Southwest Airlines
Boeing 757
Y
W
J
F
14:35
16:40
Southwest Airlines
WN 1688
Southwest Airlines
Boeing 757
Y
W
J
F
16:00
18:00
Southwest Airlines
WN 2425
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
16:05
18:05
Southwest Airlines
WN 2425
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
16:40
18:35
Southwest Airlines
WN 3319
Southwest Airlines
Boeing 757
Y
W
J
F
16:45
18:45
Southwest Airlines
WN 2425
Southwest Airlines
Boeing 757
Y
W
J
F
16:55
18:55
Southwest Airlines
WN 3319
Southwest Airlines
Boeing 757
Y
W
J
F
17:10
19:10
Southwest Airlines
WN 1218
Southwest Airlines
Boeing 757
Y
W
J
F
19:15
21:15
Southwest Airlines
WN 2434
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
20:15
22:20
Southwest Airlines
WN 2426
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
20:20
22:25
Southwest Airlines
WN 2426
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
21:15
23:15
Southwest Airlines
WN 2802
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
21:55
23:55
Southwest Airlines
WN 2802
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
21:55
23:55
Southwest Airlines
WN 2426
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
22:05
00:05
Southwest Airlines
WN 2802
Southwest Airlines
Boeing 757
Y
W
J
F
22:15
00:15
Southwest Airlines
WN 2426
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
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