Air Century
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Dominican Republic
La Isabela International Airport
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Cuba
Antonio Maceo International Airport
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Scan through all non-stop flights from Santo Domingo to Santiago de Cuba. The full flight schedule below gives an overview of all non-stop flights from JBQ to SCU, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Santiago de Cuba is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Santiago de Cuba experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Currently, there is only one airline operating non-stop flights from Santo Domingo JBQ to Santiago de Cuba SCU, which is Air Century. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their JBQ SCU flight schedule.
Flights from JBQ to SCU are operated twice a week. All flights depart at 07:00.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Santo Domingo to Santiago de Cuba takes 1 hour. The flight distance between Santo Domingo and Santiago de Cuba is 393 miles (or 632 km).
There is 1 airport in Santiago de Cuba: Antonio Maceo International Airport (SCU).
There are 2 flights per week flying from Santo Domingo to Santiago de Cuba (as of April 2026).
1 hour is the average flight time from Santo Domingo to Santiago de Cuba.
The distance from Santo Domingo to Santiago de Cuba is 393 miles (632 kilometers).
Air Century is the only airline flying nonstop from Santo Domingo to Santiago de Cuba.
There are no alliances flying direct from Santo Domingo to Santiago de Cuba at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Santo Domingo to Santiago de Cuba:
The earliest flight departs at 07:00 from Santo Domingo and arrives at 08:00 at Santiago de Cuba.
The latest flight departs at 07:00 from Santo Domingo and arrives at 08:00 at Santiago de Cuba.
393 miles (632 km) · 1h
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08:00
Air Century
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Air Century
Canadair CRJ
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