Air Century
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Cuba
Antonio Maceo International Airport
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Dominican Republic
La Isabela International Airport
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Scan through all non-stop flights from Santiago de Cuba to Santo Domingo. The full flight schedule below gives an overview of all non-stop flights from SCU to JBQ, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Santo Domingo is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Santo Domingo experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Currently, there is only one airline operating non-stop flights from Santiago de Cuba SCU to Santo Domingo JBQ, which is Air Century. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their SCU JBQ flight schedule.
Flights from SCU to JBQ are operated twice a week. Departure times vary between 09:00 - 09:15. The earliest flight departs at 09:00, the last flight departs at 09:15. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Santiago de Cuba to Santo Domingo takes 1 hour. The flight distance between Santiago de Cuba and Santo Domingo is 393 miles (or 632 km).
There are 2 airports in Santo Domingo: La Isabela International Airport (JBQ) and Las Américas International Airport (SDQ).
There are 2 flights per week flying from Santiago de Cuba to Santo Domingo (as of April 2026).
1 hour is the average flight time from Santiago de Cuba to Santo Domingo.
The distance from Santiago de Cuba to Santo Domingo is 393 miles (632 kilometers).
Air Century is the only airline flying nonstop from Santiago de Cuba to Santo Domingo.
There are no alliances flying direct from Santiago de Cuba to Santo Domingo at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Santiago de Cuba to Santo Domingo:
The earliest flight departs at 09:00 from Santiago de Cuba and arrives at 10:00 at Santo Domingo.
The latest flight departs at 09:15 from Santiago de Cuba and arrives at 10:15 at Santo Domingo.
393 miles (632 km) · 1h
09:00
10:00
Air Century
Y2 112
Air Century
Canadair CRJ
Y
W
J
F
09:15
10:15
Air Century
Y2 112
Air Century
Canadair CRJ
Y
W
J
F
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