Air Europa
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Madrid-Barajas Airport
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Bolivia
Viru Viru International Airport
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Scan through all non-stop flights from Madrid to Santa Cruz de la Sierra. The full flight schedule below gives an overview of all non-stop flights from MAD to VVI, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Santa Cruz de la Sierra is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Since Santa Cruz de la Sierra is situated south of the equator, the dry season runs from May to October. This makes it the ideal time to visit. During these months, you can expect mostly dry weather, while the wet season can bring days of rain. Temperatures remain high year-round, along with high humidity levels.
In total there are 2 airlines operating nonstop flights from Madrid MAD to Santa Cruz de la Sierra VVI. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MAD VVI flight schedule.
Flights from MAD to VVI are operated 6 times a week, with an average of 1 flight per day. Departure times vary between 02:50 - 23:35. The earliest flight departs at 02:50, the last flight departs at 23:35. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Madrid to Santa Cruz de la Sierra takes 11 hours and 15 minutes. The flight distance between Madrid and Santa Cruz de la Sierra is 5,538 miles (or 8,913 km).
There is 1 airport in Santa Cruz de la Sierra: Viru Viru International Airport (VVI).
There are 6 flights per week flying from Madrid to Santa Cruz de la Sierra (as of April 2026).
11 hours and 15 minutes is the average flight time from Madrid to Santa Cruz de la Sierra.
The distance from Madrid to Santa Cruz de la Sierra is 5,538 miles (8,913 kilometers).
Air Europa and BoA are flying nonstop from Madrid to Santa Cruz de la Sierra.
SkyTeam is currently the only alliance flying nonstop from Madrid to Santa Cruz de la Sierra.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Madrid to Santa Cruz de la Sierra:
The earliest flight departs at 02:50 from Madrid and arrives at 08:05 at Santa Cruz de la Sierra.
The latest flight departs at 23:35 from Madrid and arrives at 04:50 at Santa Cruz de la Sierra.
5,538 miles (8,913 km) · 11h 15m
02:50
08:05
Air Europa
SkyTeam
UX 25
Air Europa
Boeing 787
Y
W
J
F
14:40
19:40
BoA
OB 773
BoA
Airbus A330-200
Y
W
J
F
21:00
02:30
BoA
OB 777
BoA
Airbus A330-200
Y
W
J
F
23:35
04:50
Air Europa
SkyTeam
UX 25
Air Europa
Boeing 787
Y
W
J
F
23:35
04:50
Air Europa
SkyTeam
UX 25
Air Europa
Boeing 787-8
Y
W
J
F
23:35
04:50
Air Europa
SkyTeam
UX 25
Air Europa
Boeing 787
Y
W
J
F
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