LATAM
Did you mean flights from Cali to Medellín?
Colombia
José María Córdova International Airport
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Colombia
Alfonso Bonilla Aragón International Airport
Click to show full flight schedule
Scan through all non-stop flights from Medellín to Cali. The full flight schedule below gives an overview of all non-stop flights from MDE to CLO, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Cali is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Cali experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

In total there are 3 airlines operating nonstop flights from Medellín MDE to Cali CLO. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MDE CLO flight schedule.
Flights from MDE to CLO are operated 55 times a week, with an average of 8 flights per day. Departure times vary between 04:25 - 21:50. The earliest flight departs at 04:25, the last flight departs at 21:50. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Medellín to Cali takes 1 hour and 5 minutes. The flight distance between Medellín and Cali is 192 miles (or 309 km).
There is 1 airport in Cali: Alfonso Bonilla Aragón International Airport (CLO).
There are 55 flights per week flying from Medellín to Cali (as of April 2026).
1 hour and 5 minutes is the average flight time from Medellín to Cali.
The distance from Medellín to Cali is 192 miles (309 kilometers).
Avianca, JetSmart and LATAM are flying nonstop from Medellín to Cali.
Star Alliance is currently the only alliance flying nonstop from Medellín to Cali.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Medellín to Cali:
The earliest flight departs at 04:25 from Medellín and arrives at 05:30 at Cali.
The latest flight departs at 21:50 from Medellín and arrives at 22:55 at Cali.
192 miles (309 km) · 1h 5m
04:25
05:30
LATAM
LA 4344
LATAM
Airbus A320-100/200
Y
W
J
F
04:25
05:30
LATAM
LA 4344
LATAM
Airbus A320-100/200
Y
W
J
F
05:10
06:17
JetSmart
JA 5476
JetSmart
Airbus A320-100/200
Y
W
J
F
05:15
06:22
JetSmart
JA 5474
JetSmart
Airbus A320-100/200
Y
W
J
F
05:30
06:37
JetSmart
JA 5470
JetSmart
Airbus A320-100/200
Y
W
J
F
05:40
06:47
JetSmart
JA 5472
JetSmart
Airbus A320-100/200
Y
W
J
F
06:26
07:33
JetSmart
JA 5564
JetSmart
Airbus A320-100/200
Y
W
J
F
06:40
07:47
JetSmart
JA 5470
JetSmart
Airbus A320-100/200
Y
W
J
F
06:40
07:47
JetSmart
JA 5474
JetSmart
Airbus A320-100/200
Y
W
J
F
08:09
09:16
JetSmart
JA 5470
JetSmart
Airbus A320-100/200
Y
W
J
F
08:20
09:25
Avianca
Star Alliance
AV 9211
Avianca
Airbus A320-100/200
Y
W
J
F
08:20
09:25
Avianca
Star Alliance
AV 9211
Avianca
Airbus A319
Y
W
J
F
08:20
09:25
Avianca
Star Alliance
AV 9211
Avianca
Airbus A320-100/200
Y
W
J
F
08:20
09:25
Avianca
Star Alliance
AV 9211
Avianca
Airbus A320-100/200
Y
W
J
F
08:20
09:25
Avianca
Star Alliance
AV 9211
Avianca
Airbus A320-100/200
Y
W
J
F
08:20
09:25
Avianca
Star Alliance
AV 9211
Avianca
Airbus A319
Y
W
J
F
12:55
14:00
Avianca
Star Alliance
AV 9431
Avianca
Airbus A320-100/200
Y
W
J
F
13:46
14:53
JetSmart
JA 5474
JetSmart
Airbus A320-100/200
Y
W
J
F
14:00
15:07
JetSmart
JA 5472
JetSmart
Airbus A320-100/200
Y
W
J
F
14:30
15:37
JetSmart
JA 5476
JetSmart
Airbus A320-100/200
Y
W
J
F
14:44
15:51
JetSmart
JA 5476
JetSmart
Airbus A320-100/200
Y
W
J
F
14:45
15:52
JetSmart
JA 5476
JetSmart
Airbus A320-100/200
Y
W
J
F
15:11
16:18
JetSmart
JA 5474
JetSmart
Airbus A320-100/200
Y
W
J
F
15:25
16:32
JetSmart
JA 5472
JetSmart
Airbus A320-100/200
Y
W
J
F
16:10
17:17
JetSmart
JA 5472
JetSmart
Airbus A320-100/200
Y
W
J
F
17:45
18:52
JetSmart
JA 5474
JetSmart
Airbus A320-100/200
Y
W
J
F
18:45
19:50
Avianca
Star Alliance
AV 9471
Avianca
Airbus A320-100/200
Y
W
J
F
19:25
20:32
JetSmart
JA 5478
JetSmart
Airbus A320-100/200
Y
W
J
F
19:45
20:52
JetSmart
JA 5476
JetSmart
Airbus A320-100/200
Y
W
J
F
20:13
21:20
JetSmart
JA 5474
JetSmart
Airbus A320-100/200
Y
W
J
F
20:40
21:45
LATAM
LA 4342
LATAM
Airbus A320-100/200
Y
W
J
F
20:40
21:45
LATAM
LA 4342
LATAM
Airbus A320-100/200
Y
W
J
F
21:50
22:55
Avianca
Star Alliance
AV 9439
Avianca
Airbus A320-100/200
Y
W
J
F
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