Copa Airlines
Star Alliance
Did you mean flights from Panama City to Medellín?
Colombia
José María Córdova International Airport
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Panama
Tocumen International Airport
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Scan through all non-stop flights from Medellín to Panama City. The full flight schedule below gives an overview of all non-stop flights from MDE to PTY, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Panama City is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Panama City experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.
Currently, there is only one airline operating non-stop flights from Medellín MDE to Panama City PTY, which is Copa Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MDE PTY flight schedule.
Flights from MDE to PTY are operated 9 times a week, with an average of 1 flight per day. Departure times vary between 05:00 - 18:20. The earliest flight departs at 05:00, the last flight departs at 18:20. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Medellín to Panama City takes 1 hour and 28 minutes. The flight distance between Medellín and Panama City is 337 miles (or 542 km).
There are 3 airports in Panama City: Tocumen International Airport (PTY), Albrook "Marcos A. Gelabert" International Airport (PAC) and Howard Airport (BLB).
There are 9 flights per week flying from Medellín to Panama City (as of March 2026).
1 hour and 28 minutes is the average flight time from Medellín to Panama City.
The distance from Medellín to Panama City is 337 miles (542 kilometers).
Copa Airlines is the only airline flying nonstop from Medellín to Panama City.
Star Alliance is currently the only alliance flying nonstop from Medellín to Panama City.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Medellín to Panama City:
The earliest flight departs at 05:00 from Medellín and arrives at 06:28 at Panama City.
The latest flight departs at 18:20 from Medellín and arrives at 19:48 at Panama City.
337 miles (542 km) · 1h 28m
05:00
06:28
Copa Airlines
Star Alliance
CM 151
Copa Airlines
Boeing 737 MAX 8
Y
W
J
F
05:00
06:28
Copa Airlines
Star Alliance
CM 151
Copa Airlines
Boeing 737-800
Y
W
J
F
06:25
07:49
Copa Airlines
Star Alliance
CM 209
Copa Airlines
Boeing 737-700
Y
W
J
F
09:15
10:41
Copa Airlines
Star Alliance
CM 398
Copa Airlines
Boeing 737 MAX 8
Y
W
J
F
10:35
12:04
Copa Airlines
Star Alliance
CM 757
Copa Airlines
Boeing 737-800
Y
W
J
F
12:40
14:07
Copa Airlines
Star Alliance
CM 506
Copa Airlines
Boeing 737-800
Y
W
J
F
15:10
16:36
Copa Airlines
Star Alliance
CM 154
Copa Airlines
Boeing 737-800
Y
W
J
F
16:30
17:59
Copa Airlines
Star Alliance
CM 766
Copa Airlines
Boeing 737 MAX 8
Y
W
J
F
18:20
19:48
Copa Airlines
Star Alliance
CM 157
Copa Airlines
Boeing 737-800
Y
W
J
F
18:20
19:48
Copa Airlines
Star Alliance
CM 157
Copa Airlines
Boeing 737 MAX 9
Y
W
J
F
18:20
19:49
Copa Airlines
Star Alliance
CM 157
Copa Airlines
Boeing 737-800
Y
W
J
F
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