Southwest Airlines
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United States
Midway International Airport
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United States
Lambert-Saint Louis International Airport
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Scan through all non-stop flights from Chicago to St. Louis. The full flight schedule below gives an overview of all non-stop flights from MDW to STL, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
St. Louis is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit St. Louis any time of the year, but the best months to explore are from to and from to .
Currently, there is only one airline operating non-stop flights from Chicago MDW to St. Louis STL, which is Southwest Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MDW STL flight schedule.
Flights from MDW to STL are operated 30 times a week, with an average of 4 flights per day. Departure times vary between 05:40 - 23:00. The earliest flight departs at 05:40, the last flight departs at 23:00. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Chicago to St. Louis takes 1 hour and 20 minutes. The flight distance between Chicago and St. Louis is 251 miles (or 404 km).
There is 1 airport in St. Louis: Lambert-Saint Louis International Airport (STL).
There are 30 flights per week flying from Chicago to St. Louis (as of October 2026).
1 hour and 20 minutes is the average flight time from Chicago to St. Louis.
The distance from Chicago to St. Louis is 251 miles (404 kilometers).
Southwest Airlines is the only airline flying nonstop from Chicago to St. Louis.
There are no alliances flying direct from Chicago to St. Louis at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Chicago to St. Louis:
The earliest flight departs at 05:40 from Chicago and arrives at 06:55 at St. Louis.
The latest flight departs at 23:00 from Chicago and arrives at 00:20 at St. Louis.
251 miles (404 km) · 1h 20m
06:05
07:15
Southwest Airlines
WN 2015
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
07:50
09:00
Southwest Airlines
WN 3555
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
08:05
09:15
Southwest Airlines
WN 1353
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
08:15
09:25
Southwest Airlines
WN 372
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
08:15
09:25
Southwest Airlines
WN 1353
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
09:40
10:50
Southwest Airlines
WN 846
Southwest Airlines
Boeing 737-700
Y
W
J
F
09:55
11:05
Southwest Airlines
WN 249
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
11:05
12:15
Southwest Airlines
WN 806
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
11:25
12:35
Southwest Airlines
WN 806
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
11:50
13:00
Southwest Airlines
WN 3107
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
14:45
15:55
Southwest Airlines
WN 884
Southwest Airlines
Boeing 737-700
Y
W
J
F
14:45
15:55
Southwest Airlines
WN 494
Southwest Airlines
Boeing 737-700
Y
W
J
F
15:00
16:10
Southwest Airlines
WN 1339
Southwest Airlines
Boeing 737-700
Y
W
J
F
16:25
17:35
Southwest Airlines
WN 2016
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
16:30
17:40
Southwest Airlines
WN 4699
Southwest Airlines
Boeing 737-700
Y
W
J
F
17:50
19:00
Southwest Airlines
WN 4699
Southwest Airlines
Boeing 737-700
Y
W
J
F
19:10
20:25
Southwest Airlines
WN 670
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
20:50
22:05
Southwest Airlines
WN 2779
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
21:30
22:45
Southwest Airlines
WN 4402
Southwest Airlines
Boeing 737-700
Y
W
J
F
22:05
23:20
Southwest Airlines
WN 1687
Southwest Airlines
Boeing 737-700
Y
W
J
F
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