Aeromexico
SkyTeam
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Mexico
Mexico City International Airport
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Colombia
Alfonso Bonilla Aragón International Airport
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Scan through all non-stop flights from Mexico City to Cali. The full flight schedule below gives an overview of all non-stop flights from MEX to CLO, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Cali is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Cali experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Currently, there is only one airline operating non-stop flights from Mexico City MEX to Cali CLO, which is Aeromexico. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MEX CLO flight schedule.
Flights from MEX to CLO are operated 4 times a week, with an average of 1 flight per day. Departure times vary between 12:50 - 13:20. The earliest flight departs at 12:50, the last flight departs at 13:20. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Mexico City to Cali takes 4 hours and 55 minutes. The flight distance between Mexico City and Cali is 1,882 miles (or 3,029 km).
There is 1 airport in Cali: Alfonso Bonilla Aragón International Airport (CLO).
There are 4 flights per week flying from Mexico City to Cali (as of April 2026).
4 hours and 55 minutes is the average flight time from Mexico City to Cali.
The distance from Mexico City to Cali is 1,882 miles (3,029 kilometers).
Aeromexico is the only airline flying nonstop from Mexico City to Cali.
SkyTeam is currently the only alliance flying nonstop from Mexico City to Cali.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Mexico City to Cali:
The earliest flight departs at 12:50 from Mexico City and arrives at 18:30 at Cali.
The latest flight departs at 13:20 from Mexico City and arrives at 19:00 at Cali.
1,882 miles (3,029 km) · 4h 55m
13:00
18:55
Aeromexico
SkyTeam
AM 754
Aeromexico
Boeing 737 MAX 8
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W
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F
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