Flights from Mexico City Flights to Panama City

Direct flights from Mexico City to Panama City

Did you mean flights from Panama City to Mexico City?

Last updated on: 04-01-2026

Mexico City

Mexico

MEX

Mexico City International Airport

Panama City

Panama

PTY

Tocumen International Airport

Check Prices

Flight schedule

Distance

1,497 miles · (2,409 km)

Flight time

3 hours and 50 minutes

Airlines

Aeromexico
Copa Airlines

Alliances

Oneworld
SkyTeam
Star Alliance

Classes

Economy
Premium Economy
Business Class
First Class

Aircrafts

Boeing 737 MAX 8
Boeing 737-800
Boeing 737-800 Sky Interior
Embraer 190

Mexico City to Panama City Flight Schedule

Scan through all non-stop flights from Mexico City to Panama City. The full flight schedule below gives an overview of all non-stop flights from MEX to PTY, which includes the daily timetable of every operating airline for the upcoming 12 months.

Note: for airline-specific flight schedules, please scroll further down.

Return schedule

Best time to visit Panama City

What is the best time to visit Panama City?

🌴 Tropical

Panama City is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Being located north of the equator, Panama City experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Panama City

PTY

Airlines flying from Mexico City to Panama City

Airline-specific flight schedules from Mexico City to Panama City

In total there are 2 airlines operating nonstop flights from Mexico City MEX to Panama City PTY. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.

Click an airline below to view their MEX PTY flight schedule.

Aeromexico (AM)

Copa Airlines (CM)

Aeromexico flight schedulefrom Mexico City to Panama City

Aeromexico is a member of SkyTeam

Return schedule

Copa Airlines flight schedulefrom Mexico City to Panama City

Copa Airlines is a member of Star Alliance

Return schedule

Mexico City to Panama City Flights

Flights from MEX to PTY are operated 47 times a week, with an average of 7 flights per day. Departure times vary between 00:25 - 15:30. The earliest flight departs at 00:25, the last flight departs at 15:30. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.

You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).

The fastest direct flight from Mexico City to Panama City takes 3 hours and 50 minutes. The flight distance between Mexico City and Panama City is 1,497 miles (or 2,409 km).

Start planning your trip

Let's find you the best price for this route!

Plan a trip

Frequently asked questions - FAQ

How many airports are there in Panama City?

There are 3 airports in Panama City: Tocumen International Airport (PTY), Albrook "Marcos A. Gelabert" International Airport (PAC) and Howard Airport (BLB).