Flights from Panama City Flights to Mexico City

Direct flights from Panama City to Mexico City

Did you mean flights from Mexico City to Panama City?

Last updated on: 04-01-2026

Panama City

Panama

PTY

Tocumen International Airport

Mexico City

Mexico

MEX

Mexico City International Airport

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Flight schedule

Distance

1,497 miles · (2,409 km)

Flight time

3 hours and 57 minutes

Airlines

Aeromexico
Copa Airlines

Alliances

Oneworld
SkyTeam
Star Alliance

Classes

Economy
Premium Economy
Business Class
First Class

Aircrafts

Boeing 737 MAX 8
Boeing 737-800
Boeing 737-800 Sky Interior
Embraer 190

Panama City to Mexico City Flight Schedule

Scan through all non-stop flights from Panama City to Mexico City. The full flight schedule below gives an overview of all non-stop flights from PTY to MEX, which includes the daily timetable of every operating airline for the upcoming 12 months.

Note: for airline-specific flight schedules, please scroll further down.

Return schedule

Best time to visit Mexico City

What is the best time to visit Mexico City?

🌺 Subtropical

Famous for its year-round warmth, Mexico City often sees temperatures rise above 30°C (86°F). Relax by the water, explore lush forests, or dive into the urban scene—enjoying the perfect blend of nature, adventure, and leisure of this the subtropical destination.

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

You can visit Mexico City any time of the year, but the best time to visit is during the dry season, which runs from late September to November and again from February to early May. During those months, the weather is quite enjoyable, with warm temperatures and little rain since the wet season has ended.

Mexico City

MEX

Airlines flying from Panama City to Mexico City

Airline-specific flight schedules from Panama City to Mexico City

In total there are 2 airlines operating nonstop flights from Panama City PTY to Mexico City MEX. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.

Click an airline below to view their PTY MEX flight schedule.

Aeromexico (AM)

Copa Airlines (CM)

Aeromexico flight schedulefrom Panama City to Mexico City

Aeromexico is a member of SkyTeam

Return schedule

Copa Airlines flight schedulefrom Panama City to Mexico City

Copa Airlines is a member of Star Alliance

Return schedule

Panama City to Mexico City Flights

Flights from PTY to MEX are operated 47 times a week, with an average of 7 flights per day. Departure times vary between 09:06 - 22:15. The earliest flight departs at 09:06, the last flight departs at 22:15. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.

You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).

The fastest direct flight from Panama City to Mexico City takes 3 hours and 57 minutes. The flight distance between Panama City and Mexico City is 1,497 miles (or 2,409 km).

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Frequently asked questions - FAQ

How many airports are there in Mexico City?

There are 3 airports in Mexico City: Mexico City International Airport (MEX), Felipe Ángeles International Airport (NLU) and Lic. Adolfo López Mateos International Airport (TLC).