Copa Airlines
Star Alliance
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Tocumen International Airport
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Ecuador
Mariscal Sucre International Airport
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Scan through all non-stop flights from Panama City to Quito. The full flight schedule below gives an overview of all non-stop flights from PTY to UIO, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Quito is an oceanic/maritime destination, known for its mild summer temperatures, which are usually between 15°C and 25°C (59°F to 77°F). The winters here are refreshingly cool, without the harshness of freezing temperatures. Visitors can enjoy the green surroundings and plenty of outdoor adventures in the nearby areas, making it an excellent choice for those who enjoy temperate weather.
The best time to visit Quito is during the summer months, spanning from November to February. During this period, visitors can expect pleasant to warm temperatures, while rainfall tends to occur more frequently in the autumn and winter months, from March to August.

Currently, there is only one airline operating non-stop flights from Panama City PTY to Quito UIO, which is Copa Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their PTY UIO flight schedule.
Flights from PTY to UIO are operated twice a week. Departure times vary between 09:25 - 22:31. The earliest flight departs at 09:25, the last flight departs at 22:31. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Panama City to Quito takes 2 hours and 4 minutes. The flight distance between Panama City and Quito is 638 miles (or 1,027 km).
There is 1 airport in Quito: Mariscal Sucre International Airport (UIO).
There are 2 flights per week flying from Panama City to Quito (as of March 2026).
2 hours and 4 minutes is the average flight time from Panama City to Quito.
The distance from Panama City to Quito is 638 miles (1,027 kilometers).
Copa Airlines is the only airline flying nonstop from Panama City to Quito.
Star Alliance is currently the only alliance flying nonstop from Panama City to Quito.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Panama City to Quito:
The earliest flight departs at 09:25 from Panama City and arrives at 11:28 at Quito.
The latest flight departs at 22:31 from Panama City and arrives at 00:29 at Quito.
638 miles (1,027 km) · 2h 4m
10:29
12:32
Copa Airlines
Star Alliance
CM 829
Copa Airlines
Boeing 737-700
Y
W
J
F
10:29
12:32
Copa Airlines
Star Alliance
CM 829
Copa Airlines
Boeing 737-800
Y
W
J
F
12:06
14:10
Copa Airlines
Star Alliance
CM 714
Copa Airlines
Boeing 737-800
Y
W
J
F
15:29
17:33
Copa Airlines
Star Alliance
CM 159
Copa Airlines
Boeing 737-800
Y
W
J
F
18:40
20:44
Copa Airlines
Star Alliance
CM 152
Copa Airlines
Boeing 737-800
Y
W
J
F
22:31
00:29
Copa Airlines
Star Alliance
CM 211
Copa Airlines
Boeing 737-800
Y
W
J
F
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