Copa Airlines
Star Alliance
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Mariscal Sucre International Airport
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Tocumen International Airport
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Scan through all non-stop flights from Quito to Panama City. The full flight schedule below gives an overview of all non-stop flights from UIO to PTY, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Panama City is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Panama City experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Currently, there is only one airline operating non-stop flights from Quito UIO to Panama City PTY, which is Copa Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their UIO PTY flight schedule.
Flights from UIO to PTY are operated 5 times a week, with an average of 1 flight per day. Departure times vary between 01:30 - 18:33. The earliest flight departs at 01:30, the last flight departs at 18:33. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Quito to Panama City takes 1 hour and 56 minutes. The flight distance between Quito and Panama City is 638 miles (or 1,027 km).
There are 3 airports in Panama City: Tocumen International Airport (PTY), Albrook "Marcos A. Gelabert" International Airport (PAC) and Howard Airport (BLB).
There are 5 flights per week flying from Quito to Panama City (as of March 2026).
1 hour and 56 minutes is the average flight time from Quito to Panama City.
The distance from Quito to Panama City is 638 miles (1,027 kilometers).
Copa Airlines is the only airline flying nonstop from Quito to Panama City.
Star Alliance is currently the only alliance flying nonstop from Quito to Panama City.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Quito to Panama City:
The earliest flight departs at 01:30 from Quito and arrives at 03:27 at Panama City.
The latest flight departs at 18:33 from Quito and arrives at 20:28 at Panama City.
638 miles (1,027 km) · 1h 56m
03:08
05:05
Copa Airlines
Star Alliance
CM 153
Copa Airlines
Boeing 737-800
Y
W
J
F
06:03
07:58
Copa Airlines
Star Alliance
CM 210
Copa Airlines
Boeing 737-800
Y
W
J
F
12:26
14:23
Copa Airlines
Star Alliance
CM 799
Copa Airlines
Boeing 737-700
Y
W
J
F
14:31
16:27
Copa Airlines
Star Alliance
CM 828
Copa Airlines
Boeing 737-800
Y
W
J
F
15:10
17:07
Copa Airlines
Star Alliance
CM 718
Copa Airlines
Boeing 737-800
Y
W
J
F
18:31
20:28
Copa Airlines
Star Alliance
CM 158
Copa Airlines
Boeing 737-800
Y
W
J
F
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