Flights from Panama City Flights to Guayaquil

Direct flights from Panama City to Guayaquil

Did you mean flights from Guayaquil to Panama City?

Last updated on: 04-04-2026

Panama City

Panama

PTY

Tocumen International Airport

Guayaquil

Ecuador

GYE

José Joaquín de Olmedo International Airport

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Flight schedule

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Distance

776 miles · (1,249 km)

Flight time

2 hours and 14 minutes

Airlines

Copa Airlines

Alliances

Oneworld
SkyTeam
Star Alliance

Classes

Economy
Premium Economy
Business Class
First Class

Aircrafts

Boeing 737 MAX 8
Boeing 737 MAX 9
Boeing 737-700
Boeing 737-800

Panama City to Guayaquil Flight Schedule

Scan through all non-stop flights from Panama City to Guayaquil. The full flight schedule below gives an overview of all non-stop flights from PTY to GYE, which includes the daily timetable of every operating airline for the upcoming 12 months.

Note: for airline-specific flight schedules, please scroll further down.

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Best time to visit Guayaquil

What is the best time to visit Guayaquil?

🌴 Tropical

Guayaquil is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.

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Since Guayaquil is situated south of the equator, the dry season runs from May to October. This makes it the ideal time to visit. During these months, you can expect mostly dry weather, while the wet season can bring days of rain. Temperatures remain high year-round, along with high humidity levels.

Guayaquil

GYE

Airlines flying from Panama City to Guayaquil

Airline-specific flight schedules from Panama City to Guayaquil

Currently, there is only one airline operating non-stop flights from Panama City PTY to Guayaquil GYE, which is Copa Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.

Click an airline below to view their PTY GYE flight schedule.

Copa Airlines (CM)

Copa Airlines flight schedulefrom Panama City to Guayaquil

Copa Airlines is a member of Star Alliance

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Panama City to Guayaquil Flights

Flights from PTY to GYE are operated 40 times a week, with an average of 6 flights per day. Departure times vary between 08:20 - 21:48. The earliest flight departs at 08:20, the last flight departs at 21:48. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.

You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).

The fastest direct flight from Panama City to Guayaquil takes 2 hours and 14 minutes. The flight distance between Panama City and Guayaquil is 776 miles (or 1,249 km).

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Frequently asked questions - FAQ

How many airports are there in Guayaquil?

There is 1 airport in Guayaquil: José Joaquín de Olmedo International Airport (GYE).

How many flights per week are there from PTY to GYE?

There are 40 flights per week flying from Panama City to Guayaquil (as of April 2026).

How long does it take to fly from Panama City to Guayaquil?

2 hours and 14 minutes is the average flight time from Panama City to Guayaquil.

How far is Guayaquil from Panama City?

The distance from Panama City to Guayaquil is 776 miles (1,249 kilometers).

What airlines fly nonstop from PTY airport to GYE airport?

Copa Airlines is the only airline flying nonstop from Panama City to Guayaquil.

What alliances have direct flights from Panama City to Guayaquil?

Star Alliance is currently the only alliance flying nonstop from Panama City to Guayaquil.

What classes are available from Panama City to Guayaquil?

You can fly non-stop in Economy and Business Class.

What aircraft types fly from Panama City to Guayaquil?

Aircraft types that fly from Panama City to Guayaquil:

Boeing 737 MAX 8
Boeing 737 MAX 9
Boeing 737-700
Boeing 737-800

What is the earliest flight departing from Panama City to Guayaquil?

The earliest flight departs at 08:20 from Panama City and arrives at 10:34 at Guayaquil.

What is the latest flight available from Panama City to Guayaquil?

The latest flight departs at 21:48 from Panama City and arrives at 00:02 at Guayaquil.

Popular flights from Panama City, Panama

Panama City to Bogotá

Panama City to San José

Panama City to Punta Cana

Panama City to Miami

Panama City to Medellín

Panama City to Lima

Panama City to Mexico City

Panama City to Orlando

Panama City to Cancún

Panama City to Buenos Aires

Panama City to Guayaquil

Panama City to Guatemala City

Panama City to Santiago de Chile

Panama City to Quito

Show all flights from Panama City Show all flights to Guayaquil

Popular routes operated by Copa Airlines

Panama City to Bogotá

Panama City to San José

Panama City to Punta Cana

Panama City to Medellín

Panama City to Lima

Panama City to Miami

Panama City to Orlando

Show all Copa Airlines flights

Popular flights from Panama City via Guayaquil

Panama City to Cuenca

Panama City to Baltra Island

Panama City to San Cristóbal Island (Galápagos

Non-stop flights from PTY to GYE

776 miles (1,249 km) · 2h 14m

Round trip

1 passenger

Economy

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Return schedule

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Depart
Arrive
Airline
Flight no
Aircraft
Classes

09:08
11:22
Copa Airlines

Star Alliance
CM 273
Copa Airlines
Boeing 737-700
Y
W
J
F

09:08
11:22
Copa Airlines

Star Alliance
CM 273
Copa Airlines
Boeing 737 MAX 9
Y
W
J
F

09:08
11:22
Copa Airlines

Star Alliance
CM 273
Copa Airlines
Boeing 737-700
Y
W
J
F

09:08
11:22
Copa Airlines

Star Alliance
CM 273
Copa Airlines
Boeing 737-800
Y
W
J
F

11:21
13:35
Copa Airlines

Star Alliance
CM 258
Copa Airlines
Boeing 737-800
Y
W
J
F

11:21
13:35
Copa Airlines

Star Alliance
CM 258
Copa Airlines
Boeing 737 MAX 9
Y
W
J
F

11:21
13:35
Copa Airlines

Star Alliance
CM 258
Copa Airlines
Boeing 737-800
Y
W
J
F

11:21
13:35
Copa Airlines

Star Alliance
CM 258
Copa Airlines
Boeing 737 MAX 8
Y
W
J
F

11:21
13:35
Copa Airlines

Star Alliance
CM 258
Copa Airlines
Boeing 737-800
Y
W
J
F

15:17
17:31
Copa Airlines

Star Alliance
CM 378
Copa Airlines
Boeing 737-700
Y
W
J
F

15:17
17:31
Copa Airlines

Star Alliance
CM 378
Copa Airlines
Boeing 737 MAX 8
Y
W
J
F

15:17
17:31
Copa Airlines

Star Alliance
CM 378
Copa Airlines
Boeing 737-800
Y
W
J
F

15:17
17:31
Copa Airlines

Star Alliance
CM 378
Copa Airlines
Boeing 737-700
Y
W
J
F

15:17
17:31
Copa Airlines

Star Alliance
CM 378
Copa Airlines
Boeing 737-800
Y
W
J
F

15:17
17:31
Copa Airlines

Star Alliance
CM 378
Copa Airlines
Boeing 737-700
Y
W
J
F

18:40
20:54
Copa Airlines

Star Alliance
CM 213
Copa Airlines
Boeing 737 MAX 9
Y
W
J
F

21:24
23:38
Copa Airlines

Star Alliance
CM 301
Copa Airlines
Boeing 737-800
Y
W
J
F

21:48
00:02
Copa Airlines

Star Alliance
CM 311
Copa Airlines
Boeing 737-800
Y
W
J
F

21:48
00:02
Copa Airlines

Star Alliance
CM 311
Copa Airlines
Boeing 737-700
Y
W
J
F

21:48
00:02
Copa Airlines

Star Alliance
CM 311
Copa Airlines
Boeing 737-700
Y
W
J
F

21:48
00:02
Copa Airlines

Star Alliance
CM 311
Copa Airlines
Boeing 737-800
Y
W
J
F

21:48
00:02
Copa Airlines

Star Alliance
CM 311
Copa Airlines
Boeing 737-700
Y
W
J
F

21:48
00:02
Copa Airlines

Star Alliance
CM 311
Copa Airlines
Boeing 737-800
Y
W
J
F

21:48
00:02
Copa Airlines

Star Alliance
CM 311
Copa Airlines
Boeing 737-700
Y
W
J
F