Flights from Chicago Flights to Knoxville

Direct flights from Chicago to Knoxville

Did you mean flights from Knoxville to Chicago?

Last updated on: 10-06-2026

Chicago

United States

ORD

O'Hare International Airport

Knoxville

United States

TYS

McGhee Tyson Airport

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Flight schedule

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Distance

474 miles · (763 km)

Flight time

1 hour and 50 minutes

Airlines

American Airlines
United Airlines

Alliances

Oneworld
SkyTeam
Star Alliance

Classes

Economy
Premium Economy
Business Class
First Class

Aircrafts

Airbus A319
Airbus A320-100/200
Bombardier CRJ 550
Canadair Regional Jet 200
Canadair Regional Jet 700
Embraer 170
Embraer 175

Chicago to Knoxville Flight Schedule

Scan through all non-stop flights from Chicago to Knoxville. The full flight schedule below gives an overview of all non-stop flights from ORD to TYS, which includes the daily timetable of every operating airline for the upcoming 12 months.

Note: for airline-specific flight schedules, please scroll further down.

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Best time to visit Knoxville

What is the best time to visit Knoxville?

🌺 💦 Humid Subtropical

Knoxville is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.

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You can visit Knoxville any time of the year, but the best months to explore are from to and from to .

Knoxville

TYS

Airlines flying from Chicago to Knoxville

Airline-specific flight schedules from Chicago to Knoxville

In total there are 2 airlines operating nonstop flights from Chicago ORD to Knoxville TYS. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.

Click an airline below to view their ORD TYS flight schedule.

American Airlines (AA)

United Airlines (UA)

American Airlines flight schedulefrom Chicago to Knoxville

American Airlines is a member of Oneworld

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United Airlines flight schedulefrom Chicago to Knoxville

United Airlines is a member of Star Alliance

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Chicago to Knoxville Flights

Flights from ORD to TYS are operated 50 times a week, with an average of 7 flights per day. Departure times vary between 06:55 - 21:32. The earliest flight departs at 06:55, the last flight departs at 21:32. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.

You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).

The fastest direct flight from Chicago to Knoxville takes 1 hour and 50 minutes. The flight distance between Chicago and Knoxville is 474 miles (or 763 km).

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Frequently asked questions - FAQ

How many airports are there in Knoxville?

There is 1 airport in Knoxville: McGhee Tyson Airport (TYS).

How many flights per week are there from ORD to TYS?

There are 50 flights per week flying from Chicago to Knoxville (as of October 2026).

How long does it take to fly from Chicago to Knoxville?

1 hour and 50 minutes is the average flight time from Chicago to Knoxville.

How far is Knoxville from Chicago?

The distance from Chicago to Knoxville is 474 miles (763 kilometers).

What airlines fly nonstop from ORD airport to TYS airport?

American Airlines and United Airlines are flying nonstop from Chicago to Knoxville.

What alliances have direct flights from Chicago to Knoxville?

Oneworld and Star Alliance are flying nonstop from Chicago to Knoxville.

What classes are available from Chicago to Knoxville?

You can fly non-stop in Economy and Business Class.

What aircraft types fly from Chicago to Knoxville?

Aircraft types that fly from Chicago to Knoxville:

Airbus A319
Airbus A320-100/200
Bombardier CRJ 550
Canadair Regional Jet 200
Canadair Regional Jet 700
Embraer 170
Embraer 175

What is the earliest flight departing from Chicago to Knoxville?

The earliest flight departs at 06:55 from Chicago and arrives at 09:53 at Knoxville.

What is the latest flight available from Chicago to Knoxville?

The latest flight departs at 21:32 from Chicago and arrives at 00:28 at Knoxville.

Popular flights from Chicago, United States

Chicago to New York City

Chicago to Boston

Chicago to Los Angeles

Chicago to Washington

Chicago to Dallas-Fort Worth

Chicago to Atlanta

Chicago to San Francisco

Chicago to Denver

Chicago to Minneapolis

Chicago to Houston

Chicago to Newark

Chicago to Detroit

Chicago to Phoenix

Chicago to Seattle / Tacoma

Show all flights from Chicago Show all flights to Knoxville

Popular routes operated by American Airlines

Chicago to Dallas-Fort Worth

Chicago to Charlotte

Chicago to Washington

Chicago to New York City

Chicago to Philadelphia

Chicago to Miami

Chicago to Phoenix

Show all American Airlines flights

Popular routes operated by United Airlines

Chicago to Newark

Chicago to Houston

Chicago to Denver

Chicago to New York City

Chicago to San Francisco

Chicago to Washington

Chicago to Los Angeles

Show all United Airlines flights

Popular flights from Chicago via Knoxville

Chicago to Baton Rouge

Chicago to College Station

Chicago to Dallas

Chicago to Gulf Shores

Chicago to Houston

Chicago to Punta Gorda

Chicago to Tampa

Chicago to Orlando

Non-stop flights from ORD to TYS

474 miles (763 km) · 1h 50m

Round trip

1 passenger

Economy

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Depart
Arrive
Airline
Flight no
Aircraft
Classes

06:55
09:53
United Airlines

Star Alliance
UA 4569
United Airlines
Bombardier CRJ 550
Y
W
J
F

06:59
09:45
United Airlines

Star Alliance
UA 2035
United Airlines
Airbus A319
Y
W
J
F

06:59
09:53
United Airlines

Star Alliance
UA 4193
United Airlines
Bombardier CRJ 550
Y
W
J
F

06:59
09:45
United Airlines

Star Alliance
UA 2035
United Airlines
Airbus A319
Y
W
J
F

07:07
10:07
United Airlines

Star Alliance
UA 3636
United Airlines
Embraer 175
Y
W
J
F

08:20
11:05
American Airlines

Oneworld
AA 4229
American Airlines
Embraer 175
Y
W
J
F

10:25
13:13
United Airlines

Star Alliance
UA 4559
United Airlines
Bombardier CRJ 550
Y
W
J
F

10:25
13:13
United Airlines

Star Alliance
UA 4559
United Airlines
Bombardier CRJ 550
Y
W
J
F

10:30
13:14
United Airlines

Star Alliance
UA 4592
United Airlines
Bombardier CRJ 550
Y
W
J
F

10:30
13:14
United Airlines

Star Alliance
UA 4592
United Airlines
Bombardier CRJ 550
Y
W
J
F

10:30
13:14
United Airlines

Star Alliance
UA 4592
United Airlines
Bombardier CRJ 550
Y
W
J
F

10:30
13:14
United Airlines

Star Alliance
UA 4592
United Airlines
Bombardier CRJ 550
Y
W
J
F

10:30
13:14
United Airlines

Star Alliance
UA 4592
United Airlines
Bombardier CRJ 550
Y
W
J
F

13:15
16:02
American Airlines

Oneworld
AA 3501
American Airlines
Embraer 175
Y
W
J
F

13:15
16:02
American Airlines

Oneworld
AA 3501
American Airlines
Embraer 175
Y
W
J
F

13:15
16:02
American Airlines

Oneworld
AA 3501
American Airlines
Embraer 175
Y
W
J
F

13:25
16:12
American Airlines

Oneworld
AA 3501
American Airlines
Embraer 175
Y
W
J
F

13:31
16:18
American Airlines

Oneworld
AA 3501
American Airlines
Embraer 175
Y
W
J
F

14:07
16:57
United Airlines

Star Alliance
UA 5693
United Airlines
Bombardier CRJ 550
Y
W
J
F

14:07
16:59
United Airlines

Star Alliance
UA 5693
United Airlines
Embraer 175
Y
W
J
F

14:07
16:59
United Airlines

Star Alliance
UA 3434
United Airlines
Embraer 175
Y
W
J
F

14:10
17:10
United Airlines

Star Alliance
UA 5719
United Airlines
Canadair Regional Jet 200
Y
W
J
F

14:10
17:08
United Airlines

Star Alliance
UA 5719
United Airlines
Bombardier CRJ 550
Y
W
J
F

14:10
17:08
United Airlines

Star Alliance
UA 5719
United Airlines
Bombardier CRJ 550
Y
W
J
F

14:10
17:10
United Airlines

Star Alliance
UA 5719
United Airlines
Canadair Regional Jet 200
Y
W
J
F

14:10
17:08
United Airlines

Star Alliance
UA 5719
United Airlines
Bombardier CRJ 550
Y
W
J
F

15:29
18:20
American Airlines

Oneworld
AA 3547
American Airlines
Embraer 170
Y
W
J
F

15:29
18:20
American Airlines

Oneworld
AA 3547
American Airlines
Embraer 175
Y
W
J
F

15:29
18:20
American Airlines

Oneworld
AA 3547
American Airlines
Embraer 170
Y
W
J
F

15:29
18:20
American Airlines

Oneworld
AA 3547
American Airlines
Embraer 175
Y
W
J
F

15:29
18:20
American Airlines

Oneworld
AA 3547
American Airlines
Embraer 170
Y
W
J
F

15:29
18:20
American Airlines

Oneworld
AA 3547
American Airlines
Embraer 170
Y
W
J
F

15:29
18:20
American Airlines

Oneworld
AA 3547
American Airlines
Embraer 175
Y
W
J
F

15:30
18:21
American Airlines

Oneworld
AA 3547
American Airlines
Embraer 170
Y
W
J
F

17:59
20:54
United Airlines

Star Alliance
UA 5719
United Airlines
Embraer 175
Y
W
J
F

18:00
20:55
United Airlines

Star Alliance
UA 5719
United Airlines
Embraer 175
Y
W
J
F

18:03
20:49
United Airlines

Star Alliance
UA 795
United Airlines
Airbus A320-100/200
Y
W
J
F

18:03
20:49
United Airlines

Star Alliance
UA 795
United Airlines
Airbus A320-100/200
Y
W
J
F

18:03
20:49
United Airlines

Star Alliance
UA 795
United Airlines
Airbus A320-100/200
Y
W
J
F

18:03
20:49
United Airlines

Star Alliance
UA 795
United Airlines
Airbus A320-100/200
Y
W
J
F

18:03
20:49
United Airlines

Star Alliance
UA 795
United Airlines
Airbus A320-100/200
Y
W
J
F

18:03
20:49
United Airlines

Star Alliance
UA 795
United Airlines
Airbus A320-100/200
Y
W
J
F

18:03
21:01
United Airlines

Star Alliance
UA 5915
United Airlines
Embraer 175
Y
W
J
F

21:05
23:59
American Airlines

Oneworld
AA 4739
American Airlines
Embraer 175
Y
W
J
F

21:05
23:59
American Airlines

Oneworld
AA 4739
American Airlines
Embraer 175
Y
W
J
F

21:05
23:59
American Airlines

Oneworld
AA 4739
American Airlines
Embraer 175
Y
W
J
F

21:05
23:59
American Airlines

Oneworld
AA 4739
American Airlines
Embraer 175
Y
W
J
F

21:05
23:59
American Airlines

Oneworld
AA 4739
American Airlines
Embraer 175
Y
W
J
F