LATAM
Did you mean flights from Guayaquil to Santiago de Chile?
Chile
Comodoro Arturo Merino Benítez International Airport
Switch direction
Ecuador
José Joaquín de Olmedo International Airport
Click to show full flight schedule
Scan through all non-stop flights from Santiago de Chile to Guayaquil. The full flight schedule below gives an overview of all non-stop flights from SCL to GYE, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Guayaquil is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Since Guayaquil is situated south of the equator, the dry season runs from May to October. This makes it the ideal time to visit. During these months, you can expect mostly dry weather, while the wet season can bring days of rain. Temperatures remain high year-round, along with high humidity levels.
Currently, there is only one airline operating non-stop flights from Santiago de Chile SCL to Guayaquil GYE, which is LATAM. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their SCL GYE flight schedule.
Flights from SCL to GYE are operated 7 times a week, with an average of 1 flight per day. Departure times vary between 00:45 - 01:45. The earliest flight departs at 00:45, the last flight departs at 01:45. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Santiago de Chile to Guayaquil takes 5 hours and 18 minutes. The flight distance between Santiago de Chile and Guayaquil is 2,235 miles (or 3,597 km).
There is 1 airport in Guayaquil: José Joaquín de Olmedo International Airport (GYE).
There are 7 flights per week flying from Santiago de Chile to Guayaquil (as of April 2026).
5 hours and 18 minutes is the average flight time from Santiago de Chile to Guayaquil.
The distance from Santiago de Chile to Guayaquil is 2,235 miles (3,597 kilometers).
LATAM is the only airline flying nonstop from Santiago de Chile to Guayaquil.
There are no alliances flying direct from Santiago de Chile to Guayaquil at the moment.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Santiago de Chile to Guayaquil:
The earliest flight departs at 00:45 from Santiago de Chile and arrives at 05:03 at Guayaquil.
The latest flight departs at 01:45 from Santiago de Chile and arrives at 05:03 at Guayaquil.
2,235 miles (3,597 km) · 5h 18m
00:45
05:03
LATAM
LA 1446
LATAM
Airbus A319
Y
W
J
F
00:45
05:03
LATAM
LA 1446
LATAM
Airbus A319
Y
W
J
F
00:45
05:03
LATAM
LA 1446
LATAM
Airbus A319
Y
W
J
F
01:45
05:03
LATAM
LA 1446
LATAM
Airbus A319
Y
W
J
F
Click to Check Prices
