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Brussels Airport (Zaventem Airport)
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Scan through all non-stop flights from Samos to Brussels. The full flight schedule below gives an overview of all non-stop flights from SMI to BRU, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Brussels is an oceanic/maritime destination, known for its mild summer temperatures, which are usually between 15°C and 25°C (59°F to 77°F). The winters here are refreshingly cool, without the harshness of freezing temperatures. Visitors can enjoy the green surroundings and plenty of outdoor adventures in the nearby areas, making it an excellent choice for those who enjoy temperate weather.
The best time to visit Brussels is during the summer months, spanning from May to August. During this period, visitors can expect pleasant to warm temperatures, while rainfall tends to occur more frequently in the autumn and winter months, from September to February.

In total there are 2 airlines operating nonstop flights from Samos SMI to Brussels BRU. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their SMI BRU flight schedule.
Flights from SMI to BRU are operated twice a week. Departure times vary between 19:55 - 20:30. The earliest flight departs at 19:55, the last flight departs at 20:30. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Samos to Brussels takes 3 hours and 50 minutes. The flight distance between Samos and Brussels is 1,425 miles (or 2,293 km).
There are 2 airports in Brussels: Brussels Airport (Zaventem Airport) (BRU) and Brussels South Charleroi Airport (CRL).
There are 2 flights per week flying from Samos to Brussels (as of April 2026).
3 hours and 50 minutes is the average flight time from Samos to Brussels.
The distance from Samos to Brussels is 1,425 miles (2,293 kilometers).
Brussels Airlines and TUI Fly are flying nonstop from Samos to Brussels.
Star Alliance is currently the only alliance flying nonstop from Samos to Brussels.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Samos to Brussels:
The earliest flight departs at 19:55 from Samos and arrives at 22:45 at Brussels.
The latest flight departs at 20:30 from Samos and arrives at 23:10 at Brussels.
1,425 miles (2,293 km) · 3h 50m
19:55
22:45
TUI Fly
TB 2408
TUI Fly
Boeing 737 MAX 8
Y
W
J
F
20:30
23:10
Brussels Airlines
Star Alliance
SN 2204
Brussels Airlines
Airbus A320neo
Y
W
J
F
20:30
23:10
Brussels Airlines
Star Alliance
SN 2204
Brussels Airlines
Airbus A320-100/200
Y
W
J
F
20:30
23:10
Brussels Airlines
Star Alliance
SN 2204
Brussels Airlines
Airbus A320neo
Y
W
J
F
20:30
23:10
Brussels Airlines
Star Alliance
SN 2204
Brussels Airlines
Airbus A320-100/200
Y
W
J
F
20:30
23:10
Brussels Airlines
Star Alliance
SN 2204
Brussels Airlines
Airbus A320neo
Y
W
J
F
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