Southwest Airlines
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United States
Lambert-Saint Louis International Airport
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United States
Charleston International Airport / Charleston AFB
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Scan through all non-stop flights from St. Louis to Charleston. The full flight schedule below gives an overview of all non-stop flights from STL to CHS, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Charleston is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Charleston any time of the year, but the best months to explore are from to and from to .

Currently, there is only one airline operating non-stop flights from St. Louis STL to Charleston CHS, which is Southwest Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their STL CHS flight schedule.
Flights from STL to CHS are operated 6 times a week, with an average of 1 flight per day. Departure times vary between 08:25 - 17:20. The earliest flight departs at 08:25, the last flight departs at 17:20. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from St. Louis to Charleston takes 2 hours. The flight distance between St. Louis and Charleston is 704 miles (or 1,133 km).
There is 1 airport in Charleston: Charleston International Airport / Charleston AFB (CHS).
There are 6 flights per week flying from St. Louis to Charleston (as of April 2026).
2 hours is the average flight time from St. Louis to Charleston.
The distance from St. Louis to Charleston is 704 miles (1,133 kilometers).
Southwest Airlines is the only airline flying nonstop from St. Louis to Charleston.
There are no alliances flying direct from St. Louis to Charleston at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from St. Louis to Charleston:
The earliest flight departs at 08:25 from St. Louis and arrives at 11:25 at Charleston.
The latest flight departs at 17:20 from St. Louis and arrives at 20:15 at Charleston.
704 miles (1,133 km) · 2h
12:05
15:00
Southwest Airlines
WN 2069
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
14:10
17:05
Southwest Airlines
WN 2069
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
14:35
17:30
Southwest Airlines
WN 2069
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
17:15
20:10
Southwest Airlines
WN 3487
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
17:20
20:15
Southwest Airlines
WN 2069
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
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