Southwest Airlines
Did you mean flights from Columbus to St. Louis?
United States
Lambert-Saint Louis International Airport
Switch direction
United States
Port Columbus International Airport
Click to show full flight schedule
Scan through all non-stop flights from St. Louis to Columbus. The full flight schedule below gives an overview of all non-stop flights from STL to CMH, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Columbus is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Columbus any time of the year, but the best months to explore are from to and from to .
Currently, there is only one airline operating non-stop flights from St. Louis STL to Columbus CMH, which is Southwest Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their STL CMH flight schedule.
Flights from STL to CMH are operated 12 times a week, with an average of 2 flights per day. Departure times vary between 09:55 - 21:45. The earliest flight departs at 09:55, the last flight departs at 21:45. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from St. Louis to Columbus takes 1 hour and 20 minutes. The flight distance between St. Louis and Columbus is 408 miles (or 657 km).
There are 2 airports in Columbus: Port Columbus International Airport (CMH) and Rickenbacker International Airport (LCK).
There are 12 flights per week flying from St. Louis to Columbus (as of April 2026).
1 hour and 20 minutes is the average flight time from St. Louis to Columbus.
The distance from St. Louis to Columbus is 408 miles (657 kilometers).
Southwest Airlines is the only airline flying nonstop from St. Louis to Columbus.
There are no alliances flying direct from St. Louis to Columbus at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from St. Louis to Columbus:
The earliest flight departs at 09:55 from St. Louis and arrives at 12:15 at Columbus.
The latest flight departs at 21:45 from St. Louis and arrives at 00:05 at Columbus.
408 miles (657 km) · 1h 20m
10:15
12:35
Southwest Airlines
WN 1166
Southwest Airlines
Boeing 757
Y
W
J
F
10:15
12:40
Southwest Airlines
WN 757
Southwest Airlines
Boeing 757
Y
W
J
F
10:15
12:40
Southwest Airlines
WN 757
Southwest Airlines
Boeing 757
Y
W
J
F
10:20
12:40
Southwest Airlines
WN 2480
Southwest Airlines
Boeing 757
Y
W
J
F
10:20
12:45
Southwest Airlines
WN 757
Southwest Airlines
Boeing 757
Y
W
J
F
18:45
21:05
Southwest Airlines
WN 3059
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
18:55
21:15
Southwest Airlines
WN 3059
Southwest Airlines
Boeing 757
Y
W
J
F
19:40
22:00
Southwest Airlines
WN 2537
Southwest Airlines
Boeing 757
Y
W
J
F
19:45
22:05
Southwest Airlines
WN 2537
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
19:55
22:15
Southwest Airlines
WN 3059
Southwest Airlines
Boeing 757
Y
W
J
F
20:25
22:45
Southwest Airlines
WN 3059
Southwest Airlines
Boeing 757
Y
W
J
F
Click to Check Prices
