Southwest Airlines
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United States
Northwest Florida Regional Airport / Eglin Air Force Ba
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United States
Lambert-Saint Louis International Airport
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Scan through all non-stop flights from Destin / Fort Walton Beach to St. Louis. The full flight schedule below gives an overview of all non-stop flights from VPS to STL, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
St. Louis is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit St. Louis any time of the year, but the best months to explore are from to and from to .
Currently, there is only one airline operating non-stop flights from Destin / Fort Walton Beach VPS to St. Louis STL, which is Southwest Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their VPS STL flight schedule.
Flights from VPS to STL are operated 3 times a week, with an average of 1 flight per day. Departure times vary between 09:35 - 20:00. The earliest flight departs at 09:35, the last flight departs at 20:00. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Destin / Fort Walton Beach to St. Louis takes 1 hour and 50 minutes. The flight distance between Destin / Fort Walton Beach and St. Louis is 610 miles (or 982 km).
There is 1 airport in St. Louis: Lambert-Saint Louis International Airport (STL).
There are 3 flights per week flying from Destin / Fort Walton Beach to St. Louis (as of April 2026).
1 hour and 50 minutes is the average flight time from Destin / Fort Walton Beach to St. Louis.
The distance from Destin / Fort Walton Beach to St. Louis is 610 miles (982 kilometers).
Southwest Airlines is the only airline flying nonstop from Destin / Fort Walton Beach to St. Louis.
There are no alliances flying direct from Destin / Fort Walton Beach to St. Louis at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Destin / Fort Walton Beach to St. Louis:
The earliest flight departs at 09:35 from Destin / Fort Walton Beach and arrives at 11:25 at St. Louis.
The latest flight departs at 20:00 from Destin / Fort Walton Beach and arrives at 21:50 at St. Louis.
610 miles (982 km) · 1h 50m
10:00
12:00
Southwest Airlines
WN 1448
Southwest Airlines
Boeing 757
Y
W
J
F
10:10
12:10
Southwest Airlines
WN 2638
Southwest Airlines
Boeing 757
Y
W
J
F
15:05
17:00
Southwest Airlines
WN 1623
Southwest Airlines
Boeing 757
Y
W
J
F
16:00
18:00
Southwest Airlines
WN 1090
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
16:00
17:55
Southwest Airlines
WN 2111
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
18:40
20:40
Southwest Airlines
WN 4122
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
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