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Did you mean flights from Panama City to Santa Cruz de la Sierra?
Bolivia
Viru Viru International Airport
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Panama
Tocumen International Airport
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Scan through all non-stop flights from Santa Cruz de la Sierra to Panama City. The full flight schedule below gives an overview of all non-stop flights from VVI to PTY, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Panama City is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Panama City experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

In total there are 2 airlines operating nonstop flights from Santa Cruz de la Sierra VVI to Panama City PTY. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their VVI PTY flight schedule.
Flights from VVI to PTY are operated 11 times a week, with an average of 2 flights per day. Departure times vary between 01:12 - 11:48. The earliest flight departs at 01:12, the last flight departs at 11:48. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Santa Cruz de la Sierra to Panama City takes 4 hours and 50 minutes. The flight distance between Santa Cruz de la Sierra and Panama City is 2,152 miles (or 3,463 km).
There are 3 airports in Panama City: Tocumen International Airport (PTY), Albrook "Marcos A. Gelabert" International Airport (PAC) and Howard Airport (BLB).
There are 11 flights per week flying from Santa Cruz de la Sierra to Panama City (as of April 2026).
4 hours and 50 minutes is the average flight time from Santa Cruz de la Sierra to Panama City.
The distance from Santa Cruz de la Sierra to Panama City is 2,152 miles (3,463 kilometers).
BoA and Copa Airlines are flying nonstop from Santa Cruz de la Sierra to Panama City.
Star Alliance is currently the only alliance flying nonstop from Santa Cruz de la Sierra to Panama City.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Santa Cruz de la Sierra to Panama City:
The earliest flight departs at 01:12 from Santa Cruz de la Sierra and arrives at 05:04 at Panama City.
The latest flight departs at 11:48 from Santa Cruz de la Sierra and arrives at 15:39 at Panama City.
2,152 miles (3,463 km) · 4h 50m
01:15
05:04
Copa Airlines
Star Alliance
CM 126
Copa Airlines
Boeing 737-800
Y
W
J
F
11:48
15:39
Copa Airlines
Star Alliance
CM 220
Copa Airlines
Boeing 737-800
Y
W
J
F
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