American Airlines
Oneworld
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United States
Des Moines International Airport
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Scan through all non-stop flights from Charlotte to Des Moines. The full flight schedule below gives an overview of all non-stop flights from CLT to DSM, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Known for its continental climate, Des Moines features hot, humid summers with temperatures above 30°C (86°F) and cold, snowy winters that often drop below 0°C (32°F). This striking seasonal contrast offers travelers a variety of activities, from summer hiking to winter sports, ensuring year-round appeal.
The best time to visit Des Moines is from March to November, covering spring, summer, and fall. While summer can be hot, it also sees slightly more rainfall than other seasons.
Currently, there is only one airline operating non-stop flights from Charlotte CLT to Des Moines DSM, which is American Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their CLT DSM flight schedule.
Flights from CLT to DSM are operated 13 times a week, with an average of 2 flights per day. Departure times vary between 09:00 - 22:50. The earliest flight departs at 09:00, the last flight departs at 22:50. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Charlotte to Des Moines takes 2 hours and 36 minutes. The flight distance between Charlotte and Des Moines is 813 miles (or 1,308 km).
There is 1 airport in Des Moines: Des Moines International Airport (DSM).
There are 13 flights per week flying from Charlotte to Des Moines (as of April 2026).
2 hours and 36 minutes is the average flight time from Charlotte to Des Moines.
The distance from Charlotte to Des Moines is 813 miles (1,308 kilometers).
American Airlines is the only airline flying nonstop from Charlotte to Des Moines.
Oneworld is currently the only alliance flying nonstop from Charlotte to Des Moines.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Charlotte to Des Moines:
The earliest flight departs at 09:00 from Charlotte and arrives at 10:51 at Des Moines.
The latest flight departs at 22:50 from Charlotte and arrives at 00:17 at Des Moines.
813 miles (1,308 km) · 2h 36m
11:22
12:52
American Airlines
Oneworld
AA 2032
American Airlines
Airbus A320-100/200
Y
W
J
F
11:30
13:07
American Airlines
Oneworld
AA 1985
American Airlines
Airbus A320-100/200
Y
W
J
F
11:41
13:11
American Airlines
Oneworld
AA 2032
American Airlines
Airbus A320-100/200
Y
W
J
F
18:26
20:00
American Airlines
Oneworld
AA 1325
American Airlines
Airbus A319
Y
W
J
F
19:41
21:15
American Airlines
Oneworld
AA 3020
American Airlines
Airbus A319
Y
W
J
F
19:53
21:27
American Airlines
Oneworld
AA 3020
American Airlines
Airbus A319
Y
W
J
F
20:26
21:59
American Airlines
Oneworld
AA 1325
American Airlines
Airbus A319
Y
W
J
F
20:46
22:18
American Airlines
Oneworld
AA 3020
American Airlines
Airbus A319
Y
W
J
F
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