American Airlines
Oneworld
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United States
Des Moines International Airport
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United States
Charlotte/Douglas International Airport
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Scan through all non-stop flights from Des Moines to Charlotte. The full flight schedule below gives an overview of all non-stop flights from DSM to CLT, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Charlotte is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Charlotte any time of the year, but the best months to explore are from to and from to .
Currently, there is only one airline operating non-stop flights from Des Moines DSM to Charlotte CLT, which is American Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their DSM CLT flight schedule.
Flights from DSM to CLT are operated 13 times a week, with an average of 2 flights per day. Departure times vary between 06:39 - 18:36. The earliest flight departs at 06:39, the last flight departs at 18:36. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Des Moines to Charlotte takes 2 hours and 19 minutes. The flight distance between Des Moines and Charlotte is 813 miles (or 1,308 km).
There is 1 airport in Charlotte: Charlotte/Douglas International Airport (CLT).
There are 13 flights per week flying from Des Moines to Charlotte (as of April 2026).
2 hours and 19 minutes is the average flight time from Des Moines to Charlotte.
The distance from Des Moines to Charlotte is 813 miles (1,308 kilometers).
American Airlines is the only airline flying nonstop from Des Moines to Charlotte.
Oneworld is currently the only alliance flying nonstop from Des Moines to Charlotte.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Des Moines to Charlotte:
The earliest flight departs at 06:39 from Des Moines and arrives at 10:20 at Charlotte.
The latest flight departs at 18:36 from Des Moines and arrives at 21:55 at Charlotte.
813 miles (1,308 km) · 2h 19m
07:00
10:27
American Airlines
Oneworld
AA 2488
American Airlines
Airbus A319
Y
W
J
F
07:05
10:30
American Airlines
Oneworld
AA 2854
American Airlines
Airbus A319
Y
W
J
F
07:25
10:47
American Airlines
Oneworld
AA 2854
American Airlines
Airbus A319
Y
W
J
F
13:38
17:02
American Airlines
Oneworld
AA 2032
American Airlines
Airbus A320-100/200
Y
W
J
F
13:52
17:15
American Airlines
Oneworld
AA 1985
American Airlines
Airbus A320-100/200
Y
W
J
F
14:02
17:28
American Airlines
Oneworld
AA 2032
American Airlines
Airbus A320-100/200
Y
W
J
F
15:00
18:26
American Airlines
Oneworld
AA 2032
American Airlines
Airbus A320-100/200
Y
W
J
F
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