American Airlines
Oneworld
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United States
Des Moines International Airport
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United States
Phoenix Sky Harbor International Airport
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Scan through all non-stop flights from Des Moines to Phoenix. The full flight schedule below gives an overview of all non-stop flights from DSM to PHX, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Desert destinations like Phoenix are known for their hot days, with temperatures frequently exceeding 40°C (104°F), but cooler nights. With very little rainfall, these locations are famous for their extreme weather, breathtaking scenery, and the cultural heritage of their inhabitants. Despite the harsh living conditions, they provide a remarkable mix of adventure, calmness, and stunning landscapes, making them wonderful places to explore.
Phoenix is a wonderful destination to explore throughout the year, but it's advisable to avoid the summer months due to the intense heat. For a more enjoyable visit, plan your trip between September and May.

In total there are 3 airlines operating nonstop flights from Des Moines DSM to Phoenix PHX. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their DSM PHX flight schedule.
Flights from DSM to PHX are operated 25 times a week, with an average of 4 flights per day. Departure times vary between 05:00 - 19:55. The earliest flight departs at 05:00, the last flight departs at 19:55. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Des Moines to Phoenix takes 3 hours and 24 minutes. The flight distance between Des Moines and Phoenix is 1,147 miles (or 1,846 km).
There are 2 airports in Phoenix: Phoenix Sky Harbor International Airport (PHX) and Phoenix-Mesa Gateway Airport (AZA).
There are 25 flights per week flying from Des Moines to Phoenix (as of April 2026).
3 hours and 24 minutes is the average flight time from Des Moines to Phoenix.
The distance from Des Moines to Phoenix is 1,147 miles (1,846 kilometers).
American Airlines, Southwest Airlines and are flying nonstop from Des Moines to Phoenix.
Oneworld is currently the only alliance flying nonstop from Des Moines to Phoenix.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Des Moines to Phoenix:
The earliest flight departs at 05:00 from Des Moines and arrives at 06:25 at Phoenix.
The latest flight departs at 19:55 from Des Moines and arrives at 21:00 at Phoenix.
1,147 miles (1,846 km) · 3h 24m
05:00
06:25
American Airlines
Oneworld
AA 6188
American Airlines
Embraer 175
Y
W
J
F
05:00
06:25
American Airlines
Oneworld
AA 6188
American Airlines
Embraer 175
Y
W
J
F
05:15
06:41
American Airlines
Oneworld
AA 6188
American Airlines
Embraer 175
Y
W
J
F
05:25
06:38
American Airlines
Oneworld
AA 4015
American Airlines
Embraer 175
Y
W
J
F
05:25
06:38
American Airlines
Oneworld
AA 4015
American Airlines
Embraer 175
Y
W
J
F
05:30
06:49
American Airlines
Oneworld
AA 4956
American Airlines
Embraer 175
Y
W
J
F
12:00
13:00
Southwest Airlines
WN 869
Southwest Airlines
Boeing 757
Y
W
J
F
12:05
13:10
Southwest Airlines
WN 4248
Southwest Airlines
Boeing 757
Y
W
J
F
13:45
14:40
Southwest Airlines
WN 2132
Southwest Airlines
Boeing 757
Y
W
J
F
13:55
15:00
Southwest Airlines
WN 2497
Southwest Airlines
Boeing 737 MAX 8
Y
W
J
F
14:15
15:20
Southwest Airlines
WN 2497
Southwest Airlines
Boeing 757
Y
W
J
F
14:28
15:39
American Airlines
Oneworld
AA 2651
American Airlines
Airbus A319
Y
W
J
F
14:38
15:47
American Airlines
Oneworld
AA 2029
American Airlines
Airbus A319
Y
W
J
F
18:23
19:35
American Airlines
Oneworld
AA 3120
American Airlines
Airbus A319
Y
W
J
F
18:26
19:36
American Airlines
Oneworld
AA 3173
American Airlines
Airbus A319
Y
W
J
F
19:55
21:00
Southwest Airlines
WN 2497
Southwest Airlines
Boeing 757
Y
W
J
F
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