American Airlines
Oneworld
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Des Moines International Airport
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Los Angeles International Airport
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Scan through all non-stop flights from Des Moines to Los Angeles. The full flight schedule below gives an overview of all non-stop flights from DSM to LAX, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
The Mediterranean regions near Los Angeles are known for their warm, arid summers, where temperatures often go beyond 30°C (86°F). In some inland spots, the heat can climb even higher, sometimes reaching 40°C (104°F) or more. The winters are pleasantly mild, accompanied by some rainfall. This lovely climate, paired with breathtaking landscapes and bright, sunny days attract visitors from around the globe.
Los Angeles is a wonderful place to visit all year long, but spring (March-May) and fall (September-November) are the best seasons to visit. The weather is pleasantly warm during these times, especially since the summers can be quite hot in those regions.

Currently, there is only one airline operating non-stop flights from Des Moines DSM to Los Angeles LAX, which is American Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their DSM LAX flight schedule.
Flights from DSM to LAX are operated 7 times a week, with an average of 1 flight per day. Departure times vary between 05:45 - 18:56. The earliest flight departs at 05:45, the last flight departs at 18:56. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Des Moines to Los Angeles takes 3 hours and 58 minutes. The flight distance between Des Moines and Los Angeles is 1,443 miles (or 2,322 km).
There are 2 airports in Los Angeles: Los Angeles International Airport (LAX) and Van Nuys Airport (VNY).
There are 7 flights per week flying from Des Moines to Los Angeles (as of April 2026).
3 hours and 58 minutes is the average flight time from Des Moines to Los Angeles.
The distance from Des Moines to Los Angeles is 1,443 miles (2,322 kilometers).
American Airlines is the only airline flying nonstop from Des Moines to Los Angeles.
Oneworld is currently the only alliance flying nonstop from Des Moines to Los Angeles.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Des Moines to Los Angeles:
The earliest flight departs at 05:45 from Des Moines and arrives at 07:43 at Los Angeles.
The latest flight departs at 18:56 from Des Moines and arrives at 20:53 at Los Angeles.
1,443 miles (2,322 km) · 3h 58m
15:12
17:20
American Airlines
Oneworld
AA 6409
American Airlines
Embraer 175
Y
W
J
F
18:56
20:53
American Airlines
Oneworld
AA 5011
American Airlines
Embraer 175
Y
W
J
F
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