American Airlines
Oneworld
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Charlotte/Douglas International Airport
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United States
Florence Regional Airport
Click to show full flight schedule
Scan through all non-stop flights from Charlotte to Florence. The full flight schedule below gives an overview of all non-stop flights from CLT to FLO, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Florence is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Florence any time of the year, but the best months to explore are from to and from to .

Currently, there is only one airline operating non-stop flights from Charlotte CLT to Florence FLO, which is American Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their CLT FLO flight schedule.
Flights from CLT to FLO are operated 14 times a week, with an average of 2 flights per day. Departure times vary between 09:00 - 23:00. The earliest flight departs at 09:00, the last flight departs at 23:00. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Charlotte to Florence takes 1 hour and 3 minutes. The flight distance between Charlotte and Florence is 99 miles (or 159 km).
There is 1 airport in Florence: Florence Regional Airport (FLO).
There are 14 flights per week flying from Charlotte to Florence (as of April 2026).
1 hour and 3 minutes is the average flight time from Charlotte to Florence.
The distance from Charlotte to Florence is 99 miles (159 kilometers).
American Airlines is the only airline flying nonstop from Charlotte to Florence.
Oneworld is currently the only alliance flying nonstop from Charlotte to Florence.
You can fly non-stop in Economy only.
Aircraft types that fly from Charlotte to Florence:
The earliest flight departs at 09:00 from Charlotte and arrives at 10:21 at Florence.
The latest flight departs at 23:00 from Charlotte and arrives at 00:15 at Florence.
99 miles (159 km) · 1h 3m
14:25
15:32
American Airlines
Oneworld
AA 6003
American Airlines
Embraer RJ145
Y
W
J
F
14:43
15:50
American Airlines
Oneworld
AA 6003
American Airlines
Embraer RJ145
Y
W
J
F
16:44
17:50
American Airlines
Oneworld
AA 5983
American Airlines
Embraer RJ145
Y
W
J
F
20:40
21:47
American Airlines
Oneworld
AA 5893
American Airlines
Embraer RJ145
Y
W
J
F
21:35
22:42
American Airlines
Oneworld
AA 5893
American Airlines
Embraer RJ145
Y
W
J
F
22:54
23:57
American Airlines
Oneworld
AA 5893
American Airlines
Embraer RJ145
Y
W
J
F
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