Avianca
Star Alliance
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Ecuador
José Joaquín de Olmedo International Airport
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Colombia
José María Córdova International Airport
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Scan through all non-stop flights from Guayaquil to Medellín. The full flight schedule below gives an overview of all non-stop flights from GYE to MDE, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Medellín is an oceanic/maritime destination, known for its mild summer temperatures, which are usually between 15°C and 25°C (59°F to 77°F). The winters here are refreshingly cool, without the harshness of freezing temperatures. Visitors can enjoy the green surroundings and plenty of outdoor adventures in the nearby areas, making it an excellent choice for those who enjoy temperate weather.
The best time to visit Medellín is during the summer months, spanning from May to August. During this period, visitors can expect pleasant to warm temperatures, while rainfall tends to occur more frequently in the autumn and winter months, from September to February.
Currently, there is only one airline operating non-stop flights from Guayaquil GYE to Medellín MDE, which is Avianca. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their GYE MDE flight schedule.
Flights from GYE to MDE are operated 3 times a week, with an average of 1 flight per day. Departure times vary between 13:25 - 15:40. The earliest flight departs at 13:25, the last flight departs at 15:40. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Guayaquil to Medellín takes 1 hour and 50 minutes. The flight distance between Guayaquil and Medellín is 651 miles (or 1,048 km).
There are 2 airports in Medellín: José María Córdova International Airport (MDE) and Olaya Herrera Airport (EOH).
There are 3 flights per week flying from Guayaquil to Medellín (as of April 2026).
1 hour and 50 minutes is the average flight time from Guayaquil to Medellín.
The distance from Guayaquil to Medellín is 651 miles (1,048 kilometers).
Avianca is the only airline flying nonstop from Guayaquil to Medellín.
Star Alliance is currently the only alliance flying nonstop from Guayaquil to Medellín.
You can fly non-stop in Economy only.
Aircraft types that fly from Guayaquil to Medellín:
The earliest flight departs at 13:25 from Guayaquil and arrives at 15:10 at Medellín.
The latest flight departs at 15:40 from Guayaquil and arrives at 17:30 at Medellín.
651 miles (1,048 km) · 1h 50m
13:40
15:30
Avianca
Star Alliance
AV 8398
Avianca
Airbus A320neo
Y
W
J
F
14:05
15:55
Avianca
Star Alliance
AV 8398
Avianca
Airbus A320-100/200
Y
W
J
F
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