United Airlines
Star Alliance
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United States
George Bush Intercontinental Airport
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United States
McGhee Tyson Airport
Click to show full flight schedule
Scan through all non-stop flights from Houston to Knoxville. The full flight schedule below gives an overview of all non-stop flights from IAH to TYS, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Knoxville is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Knoxville any time of the year, but the best months to explore are from to and from to .
Currently, there is only one airline operating non-stop flights from Houston IAH to Knoxville TYS, which is United Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their IAH TYS flight schedule.
Flights from IAH to TYS are operated 27 times a week, with an average of 4 flights per day. Departure times vary between 08:00 - 20:24. The earliest flight departs at 08:00, the last flight departs at 20:24. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Houston to Knoxville takes 2 hours and 16 minutes. The flight distance between Houston and Knoxville is 770 miles (or 1,239 km).
There is 1 airport in Knoxville: McGhee Tyson Airport (TYS).
There are 27 flights per week flying from Houston to Knoxville (as of April 2026).
2 hours and 16 minutes is the average flight time from Houston to Knoxville.
The distance from Houston to Knoxville is 770 miles (1,239 kilometers).
United Airlines is the only airline flying nonstop from Houston to Knoxville.
Star Alliance is currently the only alliance flying nonstop from Houston to Knoxville.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Houston to Knoxville:
The earliest flight departs at 08:00 from Houston and arrives at 11:19 at Knoxville.
The latest flight departs at 20:24 from Houston and arrives at 23:44 at Knoxville.
770 miles (1,239 km) · 2h 16m
10:15
13:34
United Airlines
Star Alliance
UA 4887
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
10:30
13:49
United Airlines
Star Alliance
UA 4887
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
10:30
13:49
United Airlines
Star Alliance
UA 4887
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
10:30
13:49
United Airlines
Star Alliance
UA 4887
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
14:55
18:15
United Airlines
Star Alliance
UA 4890
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
14:55
18:15
United Airlines
Star Alliance
UA 4890
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
14:55
18:15
United Airlines
Star Alliance
UA 4890
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
14:55
18:11
United Airlines
Star Alliance
UA 6209
United Airlines
Embraer 175
Y
W
J
F
16:40
19:56
United Airlines
Star Alliance
UA 4017
United Airlines
Embraer 175
Y
W
J
F
20:21
23:41
United Airlines
Star Alliance
UA 4810
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
20:24
23:44
United Airlines
Star Alliance
UA 4810
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
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