United Airlines
Star Alliance
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United States
McGhee Tyson Airport
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United States
George Bush Intercontinental Airport
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Scan through all non-stop flights from Knoxville to Houston. The full flight schedule below gives an overview of all non-stop flights from TYS to IAH, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Houston is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Houston any time of the year, but the best months to explore are from to and from to .

Currently, there is only one airline operating non-stop flights from Knoxville TYS to Houston IAH, which is United Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their TYS IAH flight schedule.
Flights from TYS to IAH are operated 28 times a week, with an average of 4 flights per day. Departure times vary between 07:00 - 17:20. The earliest flight departs at 07:00, the last flight departs at 17:20. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Knoxville to Houston takes 2 hours and 37 minutes. The flight distance between Knoxville and Houston is 770 miles (or 1,239 km).
There are 2 airports in Houston: George Bush Intercontinental Airport (IAH) and William P. Hobby Airport (HOU).
There are 28 flights per week flying from Knoxville to Houston (as of April 2026).
2 hours and 37 minutes is the average flight time from Knoxville to Houston.
The distance from Knoxville to Houston is 770 miles (1,239 kilometers).
United Airlines is the only airline flying nonstop from Knoxville to Houston.
Star Alliance is currently the only alliance flying nonstop from Knoxville to Houston.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Knoxville to Houston:
The earliest flight departs at 07:00 from Knoxville and arrives at 08:24 at Houston.
The latest flight departs at 17:20 from Knoxville and arrives at 18:48 at Houston.
770 miles (1,239 km) · 2h 37m
07:05
08:46
United Airlines
Star Alliance
UA 4913
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
09:00
10:37
United Airlines
Star Alliance
UA 4038
United Airlines
Embraer 175
Y
W
J
F
11:25
13:06
United Airlines
Star Alliance
UA 4302
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
11:35
13:12
United Airlines
Star Alliance
UA 6278
United Airlines
Embraer 175
Y
W
J
F
11:40
13:21
United Airlines
Star Alliance
UA 4302
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
11:40
13:21
United Airlines
Star Alliance
UA 4302
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
15:20
16:59
United Airlines
Star Alliance
UA 4854
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
17:15
18:56
United Airlines
Star Alliance
UA 4854
United Airlines
Embraer RJ135 / RJ140 / RJ145
Y
W
J
F
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