American Airlines
Oneworld
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United States
McGhee Tyson Airport
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United States
Philadelphia International Airport
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Scan through all non-stop flights from Knoxville to Philadelphia. The full flight schedule below gives an overview of all non-stop flights from TYS to PHL, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Philadelphia is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Philadelphia any time of the year, but the best months to explore are from to and from to .
In total there are 2 airlines operating nonstop flights from Knoxville TYS to Philadelphia PHL. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their TYS PHL flight schedule.
Flights from TYS to PHL are operated 20 times a week, with an average of 3 flights per day. Departure times vary between 05:40 - 18:55. The earliest flight departs at 05:40, the last flight departs at 18:55. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Knoxville to Philadelphia takes 1 hour and 50 minutes. The flight distance between Knoxville and Philadelphia is 553 miles (or 890 km).
There is 1 airport in Philadelphia: Philadelphia International Airport (PHL).
There are 20 flights per week flying from Knoxville to Philadelphia (as of April 2026).
1 hour and 50 minutes is the average flight time from Knoxville to Philadelphia.
The distance from Knoxville to Philadelphia is 553 miles (890 kilometers).
Allegiant and American Airlines are flying nonstop from Knoxville to Philadelphia.
Oneworld is currently the only alliance flying nonstop from Knoxville to Philadelphia.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Knoxville to Philadelphia:
The earliest flight departs at 05:40 from Knoxville and arrives at 07:34 at Philadelphia.
The latest flight departs at 18:55 from Knoxville and arrives at 20:45 at Philadelphia.
553 miles (890 km) · 1h 50m
06:10
08:08
American Airlines
Oneworld
AA 6066
American Airlines
Embraer RJ145
Y
W
J
F
07:00
09:02
American Airlines
Oneworld
AA 5860
American Airlines
Embraer RJ145
Y
W
J
F
07:00
08:58
American Airlines
Oneworld
AA 5620
American Airlines
Canadair Regional Jet 900
Y
W
J
F
14:49
16:50
American Airlines
Oneworld
AA 6071
American Airlines
Embraer RJ145
Y
W
J
F
18:38
20:35
American Airlines
Oneworld
AA 5857
American Airlines
Embraer RJ145
Y
W
J
F
18:38
20:40
American Airlines
Oneworld
AA 5879
American Airlines
Embraer RJ145
Y
W
J
F
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