American Airlines
Oneworld
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United States
McGhee Tyson Airport
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United States
Miami International Airport
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Scan through all non-stop flights from Knoxville to Miami. The full flight schedule below gives an overview of all non-stop flights from TYS to MIA, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Miami is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Miami experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Currently, there is only one airline operating non-stop flights from Knoxville TYS to Miami MIA, which is American Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their TYS MIA flight schedule.
Flights from TYS to MIA are operated 7 times a week, with an average of 1 flight per day. Departure times vary between 05:15 - 19:49. The earliest flight departs at 05:15, the last flight departs at 19:49. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Knoxville to Miami takes 2 hours and 15 minutes. The flight distance between Knoxville and Miami is 725 miles (or 1,167 km).
There are 2 airports in Miami: Miami International Airport (MIA) and Opa-locka Airport (OPF).
There are 7 flights per week flying from Knoxville to Miami (as of April 2026).
2 hours and 15 minutes is the average flight time from Knoxville to Miami.
The distance from Knoxville to Miami is 725 miles (1,167 kilometers).
American Airlines is the only airline flying nonstop from Knoxville to Miami.
Oneworld is currently the only alliance flying nonstop from Knoxville to Miami.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Knoxville to Miami:
The earliest flight departs at 05:15 from Knoxville and arrives at 07:32 at Miami.
The latest flight departs at 19:49 from Knoxville and arrives at 22:00 at Miami.
725 miles (1,167 km) · 2h 15m
06:00
08:12
American Airlines
Oneworld
AA 4265
American Airlines
Embraer 175
Y
W
J
F
06:30
08:38
American Airlines
Oneworld
AA 4265
American Airlines
Embraer 175
Y
W
J
F
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