United Airlines
Star Alliance
Did you mean flights from Denver to Knoxville?
United States
McGhee Tyson Airport
Switch direction
United States
Denver International Airport
Click to show full flight schedule
Scan through all non-stop flights from Knoxville to Denver. The full flight schedule below gives an overview of all non-stop flights from TYS to DEN, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
The Mediterranean regions near Denver are known for their warm, arid summers, where temperatures often go beyond 30°C (86°F). In some inland spots, the heat can climb even higher, sometimes reaching 40°C (104°F) or more. The winters are pleasantly mild, accompanied by some rainfall. This lovely climate, paired with breathtaking landscapes and bright, sunny days attract visitors from around the globe.
Denver is a wonderful place to visit all year long, but spring (March-May) and fall (September-November) are the best seasons to visit. The weather is pleasantly warm during these times, especially since the summers can be quite hot in those regions.
In total there are 4 airlines operating nonstop flights from Knoxville TYS to Denver DEN. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their TYS DEN flight schedule.
Flights from TYS to DEN are operated 18 times a week, with an average of 3 flights per day. Departure times vary between 06:30 - 20:32. The earliest flight departs at 06:30, the last flight departs at 20:32. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Knoxville to Denver takes 3 hours and 10 minutes. The flight distance between Knoxville and Denver is 1,159 miles (or 1,865 km).
There are 2 airports in Denver: Denver International Airport (DEN) and Centennial Airport (APA).
There are 18 flights per week flying from Knoxville to Denver (as of April 2026).
3 hours and 10 minutes is the average flight time from Knoxville to Denver.
The distance from Knoxville to Denver is 1,159 miles (1,865 kilometers).
Allegiant, Frontier Airlines, Southwest Airlines and United Airlines are flying nonstop from Knoxville to Denver.
Star Alliance is currently the only alliance flying nonstop from Knoxville to Denver.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Knoxville to Denver:
The earliest flight departs at 06:30 from Knoxville and arrives at 07:36 at Denver.
The latest flight departs at 20:32 from Knoxville and arrives at 22:02 at Denver.
1,159 miles (1,865 km) · 3h 10m
08:30
10:10
United Airlines
Star Alliance
UA 5673
United Airlines
Embraer 175
Y
W
J
F
08:45
10:20
United Airlines
Star Alliance
UA 5702
United Airlines
Embraer 175
Y
W
J
F
12:20
13:40
Southwest Airlines
WN 3550
Southwest Airlines
Boeing 757
Y
W
J
F
14:40
16:05
Southwest Airlines
WN 985
Southwest Airlines
Boeing 757
Y
W
J
F
16:20
17:52
Frontier Airlines
F9 4369
Frontier Airlines
Airbus A320neo
Y
W
J
F
16:20
17:47
United Airlines
Star Alliance
UA 1588
United Airlines
Airbus A319
Y
W
J
F
16:28
18:00
Frontier Airlines
F9 4369
Frontier Airlines
Airbus A321-100/200
Y
W
J
F
16:28
18:00
Frontier Airlines
F9 4369
Frontier Airlines
Airbus A321neo
Y
W
J
F
16:30
17:56
United Airlines
Star Alliance
UA 1226
United Airlines
Boeing 737-800
Y
W
J
F
16:30
17:56
United Airlines
Star Alliance
UA 1729
United Airlines
Boeing 737-800
Y
W
J
F
Click to Check Prices
