Ryanair
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Spain
Madrid-Barajas Airport
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Italy
Casale Airport
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Scan through all non-stop flights from Madrid to Brindisi. The full flight schedule below gives an overview of all non-stop flights from MAD to BDS, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
The Mediterranean regions near Brindisi are known for their warm, arid summers, where temperatures often go beyond 30°C (86°F). In some inland spots, the heat can climb even higher, sometimes reaching 40°C (104°F) or more. The winters are pleasantly mild, accompanied by some rainfall. This lovely climate, paired with breathtaking landscapes and bright, sunny days attract visitors from around the globe.
Brindisi is a wonderful place to visit all year long, but spring (March-May) and fall (September-November) are the best seasons to visit. The weather is pleasantly warm during these times, especially since the summers can be quite hot in those regions.

Currently, there is only one airline operating non-stop flights from Madrid MAD to Brindisi BDS, which is Ryanair. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MAD BDS flight schedule.
Flights from MAD to BDS are operated twice a week. Departure times vary between 19:05 - 21:45. The earliest flight departs at 19:05, the last flight departs at 21:45. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Madrid to Brindisi takes 2 hours and 50 minutes. The flight distance between Madrid and Brindisi is 1,125 miles (or 1,811 km).
There is 1 airport in Brindisi: Casale Airport (BDS).
There are 2 flights per week flying from Madrid to Brindisi (as of April 2026).
2 hours and 50 minutes is the average flight time from Madrid to Brindisi.
The distance from Madrid to Brindisi is 1,125 miles (1,811 kilometers).
Ryanair is the only airline flying nonstop from Madrid to Brindisi.
There are no alliances flying direct from Madrid to Brindisi at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Madrid to Brindisi:
The earliest flight departs at 19:05 from Madrid and arrives at 21:55 at Brindisi.
The latest flight departs at 21:45 from Madrid and arrives at 00:35 at Brindisi.
1,125 miles (1,811 km) · 2h 50m
19:05
21:55
Ryanair
FR 5646
Ryanair
Boeing 737-800 (winglets)
Y
W
J
F
21:45
00:35
Ryanair
FR 5646
Ryanair
Boeing 737-800 (winglets)
Y
W
J
F
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