Air Europa
SkyTeam
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Madrid-Barajas Airport
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Panama
Tocumen International Airport
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Scan through all non-stop flights from Madrid to Panama City. The full flight schedule below gives an overview of all non-stop flights from MAD to PTY, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Panama City is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Panama City experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

In total there are 2 airlines operating nonstop flights from Madrid MAD to Panama City PTY. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MAD PTY flight schedule.
Flights from MAD to PTY are operated 10 times a week, with an average of 1 flight per day. Departure times vary between 15:05 - 16:00. The earliest flight departs at 15:05, the last flight departs at 16:00. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy, Premium Economy and Business Class. First Class is not available on this route (at least not as a non-stop flight).
The fastest direct flight from Madrid to Panama City takes 10 hours and 35 minutes. The flight distance between Madrid and Panama City is 5,066 miles (or 8,153 km).
There are 3 airports in Panama City: Tocumen International Airport (PTY), Albrook "Marcos A. Gelabert" International Airport (PAC) and Howard Airport (BLB).
There are 10 flights per week flying from Madrid to Panama City (as of April 2026).
10 hours and 35 minutes is the average flight time from Madrid to Panama City.
The distance from Madrid to Panama City is 5,066 miles (8,153 kilometers).
Air Europa and Iberia are flying nonstop from Madrid to Panama City.
Oneworld and SkyTeam are flying nonstop from Madrid to Panama City.
You can fly non-stop in Economy, Premium Economy and Business Class.
Aircraft types that fly from Madrid to Panama City:
The earliest flight departs at 15:05 from Madrid and arrives at 18:40 at Panama City.
The latest flight departs at 16:00 from Madrid and arrives at 20:00 at Panama City.
5,066 miles (8,153 km) · 10h 35m
15:05
18:40
Air Europa
SkyTeam
UX 55
Air Europa
Boeing 787-8
Y
W
J
F
15:05
18:40
Air Europa
SkyTeam
UX 55
Air Europa
Boeing 787-9
Y
W
J
F
15:05
18:40
Air Europa
SkyTeam
UX 55
Air Europa
Boeing 787-8
Y
W
J
F
15:05
18:40
Air Europa
SkyTeam
UX 55
Air Europa
Boeing 787-9
Y
W
J
F
15:05
18:40
Air Europa
SkyTeam
UX 55
Air Europa
Boeing 787-9
Y
W
J
F
15:05
18:40
Air Europa
SkyTeam
UX 55
Air Europa
Boeing 787-8
Y
W
J
F
15:05
18:40
Air Europa
SkyTeam
UX 55
Air Europa
Boeing 787-8
Y
W
J
F
15:05
18:40
Air Europa
SkyTeam
UX 55
Air Europa
Boeing 787-9
Y
W
J
F
15:55
20:00
Iberia
Oneworld
IB 257
Iberia
Airbus A330-200
Y
W
J
F
15:55
20:00
Iberia
Oneworld
IB 257
Iberia
Airbus A330
Y
W
J
F
16:00
20:00
Iberia
Oneworld
IB 257
Iberia
Airbus A330
Y
W
J
F
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